Linagliptin Metformin Duo Tablet 2.5/850mg

Adult dose

The dosage of this medication should be determined based on each patient's treatment regimen, efficacy, and tolerability, not exceeding the maximum recommended doses of Linagliptin 2.5 mg and Metformin 1000 mg, taken twice daily. This medication should be taken twice daily with meals. 1. If not being treated with Metformin: The initial dosage is 2.5/500 mg twice daily, one tablet each time and can be increased to 2.5/1000 mg.

This medication helps in controlling blood sugar levels. However, it should not be used in certain patients, for example, those who are allergic to the components of this medication, those with severe renal impairment, those in acute infection or shock states, those with poor liver function, and women who are pregnant or breastfeeding should not take this medication. Due to the Metformin component, this medication may cause lactic acidosis, a rare but serious side effect. Lactic acidosis is a condition caused by an excessive buildup of lactic acid in the body, which can manifest as symptoms such as difficulty breathing, abdominal pain, and lethargy. If such symptoms occur, consultation with a physician must be sought immediately, especially for patients with acute renal failure or heart disease. Additionally, there is a risk of hypoglycemia, so when taken with other blood sugar-lowering medications such as insulin or sulfonylureas, blood sugar should be monitored frequently, and medication doses adjusted according to the physician's instructions. Older adults or patients with renal impairment should undergo regular kidney function tests before and during treatment with this medication, and if kidney function falls below a certain threshold, this medication should be discontinued. This medication may cause unusual reactions such as acute pancreatitis, severe joint pain, and skin rashes, so if any of these symptoms arise, the physician should be notified immediately. During treatment, it is advisable to avoid alcohol consumption, and caution is required in dehydration or severe gastrointestinal disorders. If using iodinated contrast media for radiological exams, this medication should be discontinued for a certain period before and after the examination, and it should also be discontinued for a certain period before and after surgery. Women who are pregnant or planning to become pregnant should not use this medication and should consult a physician to find appropriate methods for blood sugar control. Finally, this medication should be stored in a safe place out of reach of children and should not be transferred to other containers; it should be stored in a moisture-free environment.

Serious side effects

Urticaria, angioedema, lactic acidosis, severe edema, pancreatitis, similar to pemphigus, angina, acute myocardial infarction, unstable angina, cardiac arrest, difficulty breathing, asthma, pulmonary embolism, liver dysfunction (jaundice), hepatitis, severe allergic reactions, severe skin adverse reactions, acute cholangitis, acute cholecystitis, cholangitis, cholelithiasis, acute renal failure, acute kidney injury, graft failure in kidney transplant, acute pyelonephritis, sepsis, severe joint pain accompanied by disability

Mild side effects

Nasopharyngitis, hypersensitivity, hypoglycemia, taste disturbance, cough, reduced appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rash, severe joint pain accompanied by disability, rhabdomyolysis, increased lipase, increased amylase, angioedema, decreased vitamin B12 and deficiency, increased serum triglycerides, increased serum creatinine, dizziness, drowsiness, fatigue, itching

This medication is sensitive to air and humidity and must be stored in a tightly sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature. Doing so will help maintain the efficacy and safety of the medication for a long time.

Appearance

Bright orange, biconvex, oval film-coated tablet

Package unit

60 tablets (10 tablets/PTP packaging x 6)