Phenob Tablet (Fenofibrate)

Adult dose

As fenofibrate, administer 160 mg orally once daily immediately after meals. Fenofibrate should be administered in conjunction with dietary management. This medication should be taken immediately after meals, as absorption may be reduced on an empty stomach.

This medication should not be administered to patients with poor liver function. Moderate to severe renal impairment patients should also avoid using it, while patients with mild renal impairment should use it cautiously with dosage adjustment or prolonged dosing intervals. It is not safe for women who are pregnant or may become pregnant, as well as breastfeeding women, to take this medication. Patients with allergies to this medication or its components should also avoid its use. Caution is required for patients with gallbladder disease or gallstones, as this medication may worsen the formation of gallstones. Patients who have experienced photosensitivity while using fibrate medications or ketoprofen should also refrain from using this medication. This medication is not intended for use in children. Patients with sclerosing cholangitis or pancreatitis should generally avoid this medication, except in cases of acute pancreatitis due to severe hyperlipidemia. This medication contains lactose and should not be administered to patients with lactose intolerance or related genetic disorders. Patients who are allergic to soybean oil, soy, peanuts, etc., should also avoid this medication. While taking this medication, liver and kidney functions should be regularly monitored, and if there is a significant increase in liver enzymes, the administration should be discontinued. If symptoms such as myalgia, muscle weakness, or increased creatine kinase levels occur, the physician should be consulted immediately, and if necessary, the drug dosage should be reduced or discontinued. In addition, skin rashes, itching, and photosensitivity reactions may occur, so sun exposure should be avoided, and any unusual symptoms should be reported. Because this medication can affect blood clotting, caution is needed for patients taking anticoagulants. When used in conjunction with other lipid-lowering agents, the risk of muscle damage can increase, so caution should be exercised. When combined with hypoglycemic agents, there is a risk of hypoglycemia, so blood glucose levels should be carefully monitored. Additionally, as this medication promotes urate excretion, dosage adjustments may be necessary when combined with urate-lowering agents. Consultation with a physician is warranted if this medication is to be taken together with oral contraceptives, as it may increase blood lipid levels. Women who are pregnant or breastfeeding should avoid this medication, especially after the third month of pregnancy due to potential harm to the fetus. Elderly patients may have decreased liver and kidney function, so careful assessment and regular function tests are needed before administration. In case of overdose, there is no specific antidote, so it is vital to adhere strictly to the prescribed dosage, and it should be kept out of the reach of children. Before starting this medication, it is essential to consult with a doctor or pharmacist, informing them of personal health conditions and any medications being taken, and to seek immediate help from a professional in case of any unusual symptoms.

Serious side effects

Hives, severe swelling (edema), chest tightness, breathing difficulties, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or breathing difficulty, asthma attacks, respiratory abnormalities accompanied by cough + fever, yellowing of the skin or eyes (jaundice), profound malaise, sudden and severe headaches, lightning-like headaches, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

Elevated serum aminotransferase levels, liver enlargement, cholestatic hepatitis, gallstones, rash, itching, photosensitivity reactions, hair loss, malaise, elevated body temperature, dizziness, headache, peripheral neuropathy, thromboembolism, elevated creatine kinase (CK), myalgia, muscle cramps, arthralgia, gastrointestinal disturbances (abdominal pain, nausea, vomiting, diarrhea, abdominal bloating), epilepsy, decreased hemoglobin, leukopenia, eosinophilia, elevated serum creatinine and urea

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, ideally at room temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained for a longer time.

Appearance

White oblong film-coated tablet

Package unit

100 tablets/box [(10 tablets/PTP*10)]