Glidam Tablet

Adult dose

This medication is administered 1 to 2 times daily before meals or with meals. Begin treatment with a low dose and adjust the dosage gradually based on blood sugar monitoring results. The starting dose in clinical trials has been glimepiride/metformin hydrochloride 2mg/500mg, and doses up to 8mg/2000mg have been administered. There is little added benefit when administering more than 4mg of glimepiride as a single agent, but some patients have shown better metabolic control with a dosage increase to 6mg or more.

This medication can cause severe lactic acidosis or hypoglycemia, so caution is necessary. Particularly, if renal function declines rapidly, the drug can accumulate in the body, increasing risk, so renal function should be monitored regularly. If dehydration symptoms or severe diarrhea, vomiting, or fever occur, it is advisable to temporarily stop taking the medication and consult a doctor. Additionally, interactions may occur when taken with other medications, so it is important to inform your healthcare provider about any medications you are currently taking. This drug is not administered to patients with insulin-dependent diabetes, acute metabolic acidosis, or severe liver or kidney impairment. Women who are pregnant or nursing should also avoid taking this medication. Elderly patients or those in poor nutritional status have a higher risk of hypoglycemia and should be observed more closely. Gastrointestinal symptoms (diarrhea, nausea, vomiting, etc.) may occur initially, but they usually improve naturally over time. If severe hypoglycemia occurs, immediately consume sugar and seek help from healthcare personnel if necessary. This medication should be monitored regularly for its effectiveness and side effects through blood glucose levels, renal function, and blood tests. Caution is required when driving or operating machinery due to possible decreased agility from hypoglycemia. Store the medication out of children's reach and do not transfer it to another container.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• severe allergic reactions
• severe lactic acidosis
• hypoglycemia
• severe rash with high fever
• blisters
• skin peeling
• mucosal pain in the mouth/eyes

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain), metallic taste, visual impairment, erythema, itching, rash, vomiting, upper abdominal discomfort, palpitations, dizziness, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, decreased vitamin B12, increased liver enzymes, hepatitis, allergic vasculitis, photosensitivity of the skin, serum sickness.

This medication should be stored in a tightly sealed container to prevent air from entering, and it is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication and prevent deterioration.

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle