Ephevana Tablet (Eperisone Hydrochloride)

Adult dose

Administer 50 mg of Eperisone Hydrochloride orally three times a day after meals. Adjust appropriately according to age and symptoms.

This medication should not be administered to certain patients. First, it should not be used in patients allergic to this medication or those with myasthenia gravis. Additionally, this medication contains lactose, so it should not be given to patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Caution is required when using this medication. Patients with a history of drug hypersensitivity or poor liver function should use this medication cautiously, as there is a risk of liver function deterioration, and conditions should be closely monitored. Although rare, shock may occur as a side effect, so patients should monitor symptoms during use and discontinue immediately if any abnormalities arise and seek appropriate treatment. Abnormal liver and kidney function, as well as blood abnormalities, may also occur infrequently, thus requiring regular condition checks. Skin rashes, itching, neurological symptoms (insomnia, drowsiness, headaches, etc.), and gastrointestinal symptoms (nausea, vomiting, loss of appetite, etc.) may also arise. Urinary symptoms such as urinary retention or incontinence, and systemic symptoms like weakness or dizziness should be observed. Severe skin adverse reactions such as Stevens-Johnson syndrome may occur, so if symptoms such as fever, erythema, blistering, itching, conjunctival injection, or stomatitis develop, the use of this medication should be discontinued immediately, and healthcare providers should be notified. During the course of this medication, symptoms such as weakness, staggering, and drowsiness may manifest, so dosage should be reduced or discontinued if symptoms are severe. Additionally, drowsiness or decreased attention may occur, hence it is advisable to avoid driving or operating hazardous machinery. Particular caution should be taken when this medication is used in conjunction with similar medications or certain muscle relaxants, as adjustment of vision may occur. Pregnant women or those who may become pregnant should use this medication only when its safety is not established and the benefits of treatment outweigh the risks. During breastfeeding, administration should be avoided if possible, and if it must be used, breastfeeding is preferably discontinued. The safety of this medication in children has not been fully established, so it has limited usage experience. Elderly patients, whose physical functions may be diminished, require special attention such as dosage adjustments.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor indicative of severe allergic reactions (including anaphylaxis)
• Severe rashes with high fever, blistering, skin peeling, oral/ocular mucosa pain (toxic epidermal necrolysis and mucocutaneous ocular syndrome)
• Angioedema
• Liver abnormalities (jaundice symptoms are not specified but include liver function deterioration and elevated ALT, AST, ALP)
• Serious neurological symptoms

Mild side effects

• Nausea
• vomiting
• loss of appetite
• abdominal discomfort
• dry mouth
• constipation
• diarrhea
• abdominal pain
• abdominal bloating
• stomatitis

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it should be kept at a temperature between 1 to 30 degrees Celsius. Proper storage will maintain the medication's effectiveness and prevent deterioration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle