Duomet XR Tablet 1000/5 mg

Adult dose

This medication is administered once daily to adults, taken with the evening meal.

This medication can rarely cause severe lactic acidosis, which may lead to death, so caution is necessary. When taken with other diabetes medications, severe hypoglycemia may occur, so it should be used with care. It should not be administered to patients who are allergic to any ingredients of this medication or have severely impaired liver function. It is also contraindicated in patients with muscle disorders or those taking certain immunosuppressants. Pregnant or breastfeeding women should not use this medication, and women of childbearing age should confirm the possibility of pregnancy and ensure appropriate contraception. The medication should be avoided in patients with severely impaired kidney function, acute heart failure, or severe infections. Before and after undergoing tests with iodine contrast agents, the administration of this medication should be temporarily discontinued, and kidney function should be reassessed before restarting. During treatment with this medication, if symptoms of muscle pain or weakness occur, the physician should be notified immediately, and blood tests may be required to check for muscle damage. Excessive alcohol intake may increase the risk of lactic acidosis, so it is advisable to avoid it. This medication requires dose adjustment based on kidney function, and regular kidney function tests should be performed. Additionally, liver function tests should also be conducted periodically to check for liver damage. It is recommended to regularly monitor blood glucose levels and vitamin B12 levels during treatment with this medication. Side effects such as gastrointestinal discomfort, muscle pain, headache, and dizziness may occur during use; if symptoms persist, consult healthcare professionals. This medication has not been established as safe or effective for use in children or adolescents under 19 years of age. Elderly patients often experience reduced kidney function; thus, careful dose adjustments and regular monitoring are necessary. In case of overdose, immediate medical attention should be sought, as this medication can be removed through hemodialysis. Caution is advised when driving or operating machinery, as dizziness may occur, and it should be kept out of reach of children. This medication should be stored in its original container, as transferring it to another container may cause degradation in quality or pose a risk of misuse.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, thrombocytopenia → severe allergic reactions. Severe rash with high fever, blisters, skin peeling, pain in the oral/eye mucosa, Stevens–Johnson syndrome, eosinophilia and systemic symptoms associated with Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) → severe skin adverse reactions. Difficulty breathing, cough accompanied by fever → respiratory problems. Yellowing of the skin or eyes (jaundice)

Mild side effects

• Diarrhea
• upper abdominal pain
• constipation
• abdominal pain
• belching
• gastroesophageal reflux disease
• upper abdominal discomfort
• indigestion
• erysipelas
• sensory disturbances

This medication should be stored in a tightly sealed container to protect it from air and moisture. The recommended storage temperature is room temperature, maintained between 1°C and 30°C.

Appearance

Yellow oval film-coated tablet

Package unit

PTP - 30 tablets/PTP[(10 tablets/PTPX3)], Bottle - 30 tablets/bottle