Epolis SR Sustained Release Tablet (Eperisone Hydrochloride)

Adult dose

This drug is a sustained release tablet and should be taken whole without crushing, splitting, or chewing. Adults should take 1 tablet (75 mg of eperisone hydrochloride) twice a day orally after meals. The dosage may be adjusted appropriately based on age and symptoms.

This drug should not be used in patients with hypersensitivity or severe myasthenia gravis. Patients with a history of hypersensitivity to the drug or with liver dysfunction should use this drug cautiously, as liver function may deteriorate, requiring careful monitoring. If allergic symptoms such as redness, itching, hives, swelling, or difficulty breathing occur while taking this drug, immediately discontinue administration and receive appropriate treatment. Serious skin reactions such as toxic epidermal necrolysis or Stevens-Johnson syndrome may occur, so symptoms such as fever, erythema, blisters, itching, conjunctival injection, and oral mucositis should be closely monitored, and the drug should be discontinued if these symptoms arise. Regularly monitor for any abnormalities that may occur in the liver or kidneys, and discontinue administration if any issues are found. This drug may cause various side effects such as dizziness, headache, drowsiness, nausea, vomiting, constipation, diarrhea, and abdominal pain, so if symptoms are severe, consult a physician. Drowsiness or decreased concentration may occur during use, so avoid driving or operating dangerous machinery. Women who are pregnant or may become pregnant should only use this drug if the benefits outweigh the risks, as its safety has not been established, and breastfeeding should be avoided during treatment or discontinued if necessary. Caution is needed when using in children as safety has not been sufficiently established. Elderly patients may have decreased physical functions and should use with caution, including dose adjustment if necessary. Additionally, concomitant use with other drugs containing similar ingredients or certain muscle relaxants may lead to impaired coordination, so consult with a physician or pharmacist.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, shock, anaphylactic reactions, redness, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, toxic epidermal necrolysis (Lyell syndrome), Stevens-Johnson syndrome (mucocutaneous syndrome), fever, erythema, ocular congestion, oral mucositis, liver function impairment, severe allergic reactions, serious skin adverse reactions, respiratory issues, liver abnormalities (jaundice), severe swelling or abdominal distension

Mild side effects

• Redness
• itching
• swelling
• oral mucositis
• insomnia
• drowsiness
• headache
• limb paralysis
• muscle stiffness
• limb tremors

This drug should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is advisable to store the drug at room temperature (between 1°C and 30°C), avoiding extreme cold or heat.

Appearance

White to almost white round sustained release film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle