Ranitidine 150 mg (Ranitidine Hydrochloride)

Adult dose

For adults, a single dose of 150 mg of ranitidine is orally administered twice a day, in the morning and at bedtime. For gastric and duodenal ulcers, 150 mg may be taken twice a day or 300 mg may be taken once daily at bedtime. For patients with duodenal ulcers, 300 mg can be taken twice a day, in the morning and at bedtime. This medication is used to prevent ulcers caused by NSAID administration or in combination therapy.

Child dose

For children aged 8 to 18 years, a single dose of 150 mg (2 mg per kg of body weight) may be administered up to twice a day.

This drug should not be used in patients with a history of hypersensitivity to its components or acute porphyria. In patients with impaired renal function, the blood concentration of this drug may increase, so it should be used with caution by reducing the dose or increasing the dosage interval. Caution is also needed in patients with impaired liver function. Patients with a history of hypersensitivity, elderly patients, and patients taking NSAIDs should have their condition monitored regularly while taking this medication. Since this drug may mask symptoms of gastric cancer, patients with gastric ulcers or middle-aged patients with newly occurring dyspepsia should only use it after confirming there is no malignancy. For patients with Helicobacter pylori-associated gastric and duodenal ulcers, it is recommended to also conduct eradication therapy. This drug can rarely cause serious allergic reactions, blood abnormalities, liver dysfunction, gastrointestinal symptoms, neurological abnormalities, skin rashes, and various side effects, so if unusual symptoms appear, the drug should be stopped immediately and a doctor consulted. It is important to regularly check for abnormalities through blood tests and liver-kidney function tests during treatment. Elderly patients, patients with chronic lung disease, diabetes, and those with weakened immune systems may have an increased risk of pneumonia when taking this medication. If dizziness or drowsiness occurs after taking this drug, it is safer to avoid driving or operating hazardous machinery. Furthermore, this drug can affect the absorption or metabolism of other medications, so if you are taking other drugs, you must consult a doctor or pharmacist. In pregnant or breastfeeding women, the effects of this drug on the fetus or baby are not fully known, so it should be used cautiously only when necessary. Safety for children has not been adequately established, thus special precautions are needed for pediatric patients. In case of overdose, measures such as vomiting or gastric lavage should be taken, and if necessary, hemodialysis can be performed to remove the drug, so inform medical staff immediately in emergencies. This drug should be stored out of reach of children, and it is advisable not to transfer it to other containers. Long-term use could affect the eyes, so regular ophthalmologic examinations are recommended.

Serious side effects

• Anaphylactic shock
• urticaria
• angioedema
• bronchospasm
• chest pain
• hypotension
• vascular edema
• leukopenia
• thrombocytopenia
• bone marrow suppression

Mild side effects

• Rash
• fever
• hypotension
• chest pain
• elevated serum creatinine levels
• bradycardia
• atrioventricular block
• tachycardia
• vasculitis
• constipation

This medicine should be stored in a tightly sealed container to prevent air from entering, and it is best kept in a dry place at room temperature between 1°C and 30°C. By storing it this way, the effectiveness of the medication can be maintained for a long time.

Appearance

White round film-coated tablet

Package unit

100 tablets/PTP[(10 tablets/PTP*10)], 300 tablets/bottle