Medication info
Expira Tablet 10/160 mg

Expira Tablet 10/160 mg

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›13.87mg / 1 tabletValsartan›160mg / 1 tablet
Manufacturer / importer
(주)테라젠이텍스
Appearance
Bright yellow oval film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 201905461 · Approved 2019.07.31 · Insurance code 698504010

Summary

Main use
Improvement of blood pressure control in essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dosage is one tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning).
Child dose
Safety and efficacy in pediatric patients under 18 years of age have not been established, and the use of this medication is not recommended.

Ingredients

Manufacturer
(주)테라젠이텍스

Efficacy & effects

Improvement of blood pressure control in essential hypertension

  • Essential hypertension
View approved original text

Some patients with essential hypertension may find it difficult to control blood pressure with either amlodipine or valsartan monotherapy alone. In these cases, combining both medications can lower blood pressure more effectively. Amlodipine helps to lower blood pressure by dilating blood vessels, while valsartan aids in blood pressure control by inhibiting blood vessel constriction. This combination therapy contributes to reducing cardiovascular risks associated with hypertension. Therefore, this medication is used for the treatment of essential hypertension.

How to take

Adult dose

The recommended dosage is one tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning).

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established, and the use of this medication is not recommended.

Precautions

This medication can cause serious harm or be fatal to the fetus if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Do not use if allergic to this medication or similar drugs, nor should it be taken by pregnant or breastfeeding women. Patients with severely impaired kidney function, severe liver damage, or certain heart conditions may be at risk when taking this medication, so caution is necessary. In cases of decreased sodium or fluid in the body, there is a risk of excessively low blood pressure, so it is important to check the status before taking the medication and closely monitor blood pressure and symptoms during treatment. Patients with high potassium levels should have regular blood tests when taking this medication along with potassium supplements, as potassium levels may further increase. Patients with vascular issues in the kidneys or those who have undergone kidney transplants may have worsening kidney function while taking this medication, requiring careful management by a physician. If symptoms of angioedema, such as swelling of the face, lips, or tongue, occur during treatment, discontinue the medication immediately and consult with healthcare professionals. Patients with heart failure or post-myocardial infarction should be especially cautious about changes in kidney function and blood pressure while taking this medication, and regular monitoring of kidney function is necessary. The risk of hypotension, kidney function decline, and hyperkalemia can increase when this medication is taken with other antihypertensive agents, so it is essential to discuss drug interactions with a physician or pharmacist. Dizziness or fatigue may occur while driving or operating machinery, so caution is advised. In cases of overdose, severe hypotension or cardiac rhythm abnormalities may occur, so it is important to adhere to the prescribed dosage and seek medical attention immediately if abnormal symptoms arise. This medication is not recommended for children under 18 years of age as safety and efficacy have not been established. For the elderly, it should be administered at similar doses to those for adults, but careful observation should be conducted considering the individual's physical condition. It is important to regularly check blood pressure, kidney function, and electrolyte levels during treatment to confirm normal status.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (including angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blistering, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning-like headache, seizures, confusion, vision changes

Mild side effects

  • Headache
  • dizziness
  • drowsiness
  • sensory disturbance
  • vertigo
  • tinnitus
  • tachycardia
  • palpitations
  • fainting
  • orthostatic hypotension
Show 28 more
  • hypotension
  • cough
  • throat and laryngeal pain
  • diarrhea
  • nausea
  • abdominal pain
  • constipation
  • dry mouth
  • rash
  • erythema
  • sweating
  • itching
  • joint swelling
  • low back pain
  • arthritis
  • muscle cramps
  • weakness
  • frequent urination
  • polyuria
  • erectile dysfunction
  • edema
  • peripheral edema
  • facial swelling
  • fatigue
  • flushing
  • weakness
  • facial flushing
  • nasal congestion

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container to prevent exposure to air or moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. Proper storage will safely preserve the medication's effectiveness.

Appearance and packaging

Appearance

Bright yellow oval film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.