Hyaluem Injection (Pre-filled) (Sodium Hyaluronate)

Adult administration

Usually, one tube is injected into the knee joint or shoulder joint once a week for three consecutive weeks in adults, but the injection frequency should be adjusted according to symptoms.

This medication should not be used in patients who have previously experienced allergic reactions to its ingredients. It should be used with caution in patients who have had allergic reactions to other medications, have liver function issues or a history of liver disease, and in patients with skin diseases or infections at the site of injection. Serious shock symptoms may occur with the use of this medication; therefore, the patient's condition should be closely monitored after administration, and if abnormal symptoms arise, administration should be immediately stopped, and appropriate treatment should be provided. Additionally, allergic symptoms such as swelling or redness around the face or eyes, rashes, hives, and itching may appear; if such symptoms occur, medication use should be stopped, and treatment should be sought. Temporary pain, swelling, redness, warmth, and a feeling of pressure may occur at the injection site in the joint, and rarely, symptoms of joint effusion may also appear. Other symptoms such as nausea, vomiting, and fever may also occur, and if these symptoms arise, the healthcare professional should be informed. In patients with severe inflammation due to degenerative knee disease, it is advisable to reduce inflammation before use of this medication, and measures to stabilize the joint should be taken after administration. If the medication leaks out of the joint, it may cause pain, so it must be injected accurately into the joint. Aseptic technique must be maintained during injection, and if symptoms do not improve, administration should be limited to a maximum of three times and then stopped. If there is excess joint fluid, a procedure to remove the joint fluid may be necessary before injection. This medication should not be injected into blood vessels and is not used for eye treatments. A syringe with a gauge size of 22-23 is appropriate, and caution should be exercised as the medication may precipitate when used with certain disinfectants. The safety of this medication during pregnancy has not been fully established, hence it should be used cautiously only when the benefits outweigh the risks in women who are pregnant or may become pregnant. Furthermore, since this medication can be transmitted through breast milk, it is advisable to avoid breastfeeding during treatment. The safety of this medication in children has not been established, so it should be used cautiously only when necessary. Elderly patients may have decreased physical function, so extra caution is required during use.

Serious side effects

Shock symptoms (severe allergic reaction).

Mild side effects

• Facial swelling
• facial redness
• rash
• hives
• itching
• pain
• swelling
• effusion
• redness
• warmth

This medication should be stored in a sealed container that allows no air to enter, at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

A colorless, transparent, and viscous liquid contained in a glass or plastic tube (pre-filled syringe) sealed with rubber stoppers on both ends.

Package unit

2.0mL/tube X 3