Bontroda Capsule 50mg (DIASELEIN)

Adult dose

Adults: Administer 50∼100mg of diacerein per day orally after meals in 1∼2 divided doses. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily is recommended for the first 2-4 weeks, followed by 50mg twice daily.

This medication should not be used by patients with inflammatory bowel disease. In particular, it should not be administered to patients with ulcerative colitis or Crohn's disease. Patients with intestinal obstruction syndrome or unexplained abdominal pain should also avoid taking this medication. People who have allergies to this medicine, its ingredients, or Rhein-type drugs should avoid using it. It is advisable for patients with liver diseases or those who have previously suffered from liver diseases not to take this drug. This medication is not for use in children under 15 years of age. It contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. This medication should be used cautiously in patients with a history of small intestine or colon disease. Women who are pregnant or breastfeeding should also be careful when using this drug. Additionally, elderly patients over 65 years should use a reduced dosage. Taking this medication may lead to gastrointestinal symptoms such as diarrhea, loose stools, and abdominal pain. With prolonged use, serious problems such as gastrointestinal bleeding, ulcers, or perforation may occur, so caution is required. Rarely, pigmentation of the rectal mucosa may occur. If severe diarrhea occurs, dehydration or electrolyte imbalance may take place, so one should consult a doctor immediately if symptoms arise. Symptoms like itching, rash, and eczema may frequently occur on the skin. There can also be cases of liver function abnormalities, so it is advisable to regularly check liver enzyme levels. When taking this medication for a long time, it is essential to follow the doctor's instructions. If diarrhea develops, stop taking it and follow the doctor's instructions, avoiding using with laxatives. If signs of liver damage appear, stop taking immediately and consult a doctor, and it is advisable to limit alcohol intake. This medicine may be impeded in absorption if taken with antacids containing calcium, magnesium, or aluminum, or with salt, so it should be taken at least 2 hours apart. Taking it with diuretics may enhance the diuretic effect and increase the risk of dehydration and hypokalemia, so caution is needed. Additionally, using it in combination with cardiac glycosides may increase the risk of arrhythmia, so caution is also required. Pregnant women should preferably avoid this medication as it may affect fetal bone formation. Breastfeeding women should also avoid it, as the components may transfer to breast milk in small amounts, making it safer to refrain from using it. In case of overdose, severe diarrhea may occur, and appropriate treatment such as electrolyte replenishment is necessary.

• Diarrhea
• loose stools
• abdominal pain
• gastrointestinal disorders
• bleeding
• ulcers
• perforation
• pigmentation of the rectal mucosa
• itching
• rash

Store this medication in a tightly closed container to prevent exposure to air or moisture. It is best to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance

A hard capsule with a white upper part and yellow lower part filled with brownish-yellow contents.

Package unit

30 capsules/bottle, 500 capsules/bottle