Medication info
DIASETRIN Capsule (Diacerein)

DIASETRIN Capsule (Diacerein)

Prescription medicationHard capsuleOral
Ingredient · strength
Diacerein›50mg / 1 capsule
Manufacturer / importer
Daewoo Pharmaceutical Co., Ltd.
Appearance
A hard capsule filled with a yellowish-brown substance, with a white upper part and yellow lower part.
Packaging
30 capsules/bottle, 500 capsules/bottle
Approval status
Active

MFDS item code 201905329 · Approved 2019.07.26

Summary

Main use
Treatment of osteoarthritis (hip and knee)
Who takes it
Adults
Adult dose
Adults: Administer 50∼100mg of diacerein per day orally in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

Ingredients

Manufacturer
Daewoo Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of osteoarthritis (hip and knee)

  • Osteoarthritis
  • hip joint arthritis
  • knee joint arthritis
  • arthrosis
  • degenerative joint disease
View approved original text

Arthritis of the hip and knee joints causes pain and restricted movement due to degenerative changes in the joint tissues. This medication helps to reduce inflammation in the joints and alleviate pain, improving discomfort in daily life. It also enhances joint function, increases the range of motion, and helps to slow down damage to joint structures. It acts effectively on degenerative joint diseases and improves the quality of life. Therefore, this medication is used for the treatment of arthritis in the hip and knee joints.

How to take

Adult dose

Adults: Administer 50∼100mg of diacerein per day orally in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

Precautions

This medication should not be used in patients with inflammatory bowel disease, those with intestinal obstruction syndrome, or patients with unexplained abdominal pain. Additionally, it should not be administered to patients who are allergic to this drug, its ingredients, or Rhein-class medications. Patients with hepatic disease or a history of hepatic disease, as well as children under 15 years of age, should also not receive this medication. This drug contains lactose, so it should not be used in patients with lactose intolerance or specific genetic metabolic disorders. Patients with a history of small intestine or colon diseases should use this medication with caution, as should pregnant or breastfeeding women. Elderly patients over 65 years of age should take this medication at a reduced dose. Long-term use of this medication must be done under a physician's direction; if diarrhea occurs, it should be stopped immediately, and a doctor should be consulted as dehydration and electrolyte imbalance may occur. Hepatic function abnormalities may occur, so it is advisable to periodically monitor liver health, and it is best to avoid alcohol consumption. This medication may interfere with the absorption of antacids containing calcium, magnesium, or aluminum; therefore, they should be taken with a gap of at least 2 hours apart. Caution is advised when taken together with diuretics, as there may be a risk of dehydration and hypokalemia, and increased risk of arrhythmia when combined with cardiac glycosides. Pregnant or breastfeeding women should avoid using this medication as it may affect the fetus or newborn. In case of overdose, severe diarrhea may occur, necessitating electrolyte replenishment and other necessary treatments.

Side effects

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (hemorrhage, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rash, eczema, elevation of serum liver enzymes

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a sealed container to prevent exposure to air or moisture, and keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

A hard capsule filled with a yellowish-brown substance, with a white upper part and yellow lower part.

Package unit

30 capsules/bottle, 500 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.