Hyaluric Injection (Pre-filled) (Sodium Hyaluronate)

Adult dosage

Typically administered to adults once a week, one vial for three consecutive weeks into the knee joint or shoulder joint (shoulder joint cavity, subacromial bursa, or bicipital tendon sheath), but the frequency of administration should be adjusted according to symptoms. This medication is administered intra-articularly, so it should be performed under strict aseptic conditions.

This medication should not be used in patients who have had allergic reactions to its components. It should also be used cautiously in patients who have had allergic reactions to other medications or have liver function issues or a history of liver disease. Care should be taken if there are skin diseases or infections in the joint area, as this medication is injected directly into the joint. When using this medication, it is crucial to monitor the patient closely, as severe side effects such as shock may occur. If any abnormal symptoms appear, discontinue use immediately and seek appropriate treatment. Additionally, allergy symptoms such as swelling of the face or around the eyes, rash, or itching may appear; if these symptoms occur, use should be stopped. Temporary pain, swelling, redness, warmth, and severe pressure can occur at the injection site. Sometimes symptoms like nausea, vomiting, and fever may also occur, so caution is advised. If the joint is severely inflamed, it is advisable to treat the inflammation first before using this medication. Stabilizing the injection site post-injection can be helpful. If this medication leaks outside the joint, it may cause pain, so it must be injected accurately into the joint. Strict aseptic technique must be maintained during injection, and if symptoms do not improve, administration should be limited to three doses and then discontinued. If there is excessive fluid in the joint, aspiration prior to injection may be necessary. This medication is not suitable for intravenous use or ocular application. Using an injection needle of size 22-23 gauge is recommended. Also, care should be taken as mixing with certain disinfectants may cause precipitation of the drug. Pregnant women or those who may become pregnant should carefully weigh the benefits and risks of using this medication, and it is best to avoid use during breastfeeding. For children, safety has not been established, so it should be used cautiously only when necessary. Elderly patients may have impaired bodily functions, thus requiring even more careful use.

Serious side effects

Shock symptoms (severe allergic reaction).

Mild side effects

• Facial swelling
• eyelid swelling
• facial flushing
• rash
• hives
• itching
• transient pain
• swelling
• redness
• warmth

This medication should be stored in a sealed container that prevents air ingress, ideally at room temperature between 1 and 30 degrees Celsius. This will help maintain the drug's efficacy and ensure safe usage.

Appearance

A pre-filled injectable solution containing a colorless, transparent, viscous liquid inside a glass vial sealed with rubber stoppers at both ends (part of a pre-filled syringe system).

Package unit

2ml/vial x 3