Medication info
Uotan Tablet 160/12.5 mg

Uotan Tablet 160/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Valsartan›160mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)옵투스제약
Appearance
Dark red oval film-coated tablet
Packaging
28 tablets (14 tablets/2 PTP packages)
Approval status
Active

MFDS item code 201905312 · Approved 2019.07.25 · Insurance code 649702460

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults
Adult dose
The recommended adult dosage is 1 tablet of Valsartan 80 mg/Hydrochlorothiazide 12.5 mg once daily, to be taken with a small amount of water regardless of meals. Valsartan 160 mg/Hydrochlorothiazide 12.5 mg is used when prescribed for blood pressure lowering. No dose adjustment is needed for patients with mild to moderate kidney impairment. Patients with liver impairment should not exceed 80 mg of Valsartan daily if they have mild to moderate liver impairment without bile duct obstruction.

Ingredients

Manufacturer
(주)옵투스제약

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential hypertension
View approved original text

This medication is used for patients with essential hypertension whose blood pressure is not sufficiently controlled by monotherapy. It effectively lowers blood pressure, reduces cardiovascular risks, and helps maintain a healthy blood pressure state.

How to take

Adult dose

The recommended adult dosage is 1 tablet of Valsartan 80 mg/Hydrochlorothiazide 12.5 mg once daily, to be taken with a small amount of water regardless of meals. Valsartan 160 mg/Hydrochlorothiazide 12.5 mg is used when prescribed for blood pressure lowering. No dose adjustment is needed for patients with mild to moderate kidney impairment. Patients with liver impairment should not exceed 80 mg of Valsartan daily if they have mild to moderate liver impairment without bile duct obstruction.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. This medication should not be used in cases of allergy to this drug or its components, or in individuals with certain liver or kidney impairment. Patients with electrolyte imbalance, impaired kidney or liver function, the elderly, and those with diabetes should use this medication with extra caution. Dizziness or drowsiness may occur while taking this medication, so caution is advised when driving or operating machinery. Potassium supplements or potassium-containing medications should not be taken together without consulting a physician, and regular monitoring of blood electrolyte levels is important. This medication may increase sensitivity to sunlight or UV rays; therefore, sunscreen and protection should be used while taking it. Rarely, severe allergic reactions, angioedema, hepatitis, renal failure, electrolyte abnormalities, etc., may occur during treatment, so any unusual symptoms should be reported to medical personnel immediately. Drug interactions may occur, so inform your physician or pharmacist of any current medications being taken. In case of overdose, symptoms such as hypotension, arrhythmias, and electrolyte imbalances may occur, requiring immediate medical attention. Keep out of reach of children, store in a dry place, and keep in the original container.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, angioedema, severe allergic reactions, symptoms resembling anaphylaxis, hepatitis, liver abnormalities (jaundice), renal failure, severe edema or urination problems, hyperkalemia, hyponatremia, shock, fainting, loss of consciousness, agranulocytosis, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia, necrotizing vasculitis, toxic epidermal necrolysis (Lyell's syndrome), interstitial pneumonia, lung

Mild side effects

  • Headache
  • dizziness
  • nasopharyngitis
  • fatigue
  • lumbago
  • cough
  • upper respiratory infection
  • diarrhea
  • arthralgia
  • abdominal pain
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  • epigastric pain
  • blurred vision
  • visual disturbances
  • anxiety
  • arthritis
  • bronchitis
  • acute bronchitis
  • chest pain
  • orthostatic dizziness
  • dry mouth
  • dyspepsia
  • erectile dysfunction
  • enterocolitis
  • sweating
  • paresthesia
  • insomnia
  • hypokalemia
  • hypotension
  • influenza
  • muscle cramps
  • myalgia
  • nausea
  • nasal congestion
  • nasal bleeding
  • throat pain
  • otitis media

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture; therefore, it should be stored in an airtight container in a cool place below 30 degrees Celsius. Doing so will help maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

Dark red oval film-coated tablet

Package unit

28 tablets (14 tablets/2 PTP packages)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.