Myungmoon Linagliptin Duo Tablet 2.5/500 mg

Adult dose

The dosage of this medication is determined based on the maximum recommended doses of each component, which are linagliptin 2.5 mg and metformin 1000 mg, not exceeding twice a day, while considering each patient's current treatment regimen, effectiveness, and tolerance. This medication is taken twice a day with meals. 1. If not currently being treated with metformin: Take this medication 2.5/500 mg twice a day, 1 tablet at a time, and can increase to 2.5/1000 mg twice a day.

This medication helps in controlling blood sugar. However, since a serious side effect known as lactic acidosis can occur, it should not be used in patients with impaired kidney function or severe liver dysfunction. Additionally, patients with serious cardiac or pulmonary impairment such as acute myocardial infarction, shock, or heart failure should not take this medication. Women who are pregnant or breastfeeding should also avoid this medication. During treatment, symptoms of hypoglycemia may occur, so it is important to carefully monitor blood sugar changes, especially if taking insulin or sulfonylureas concurrently. If symptoms such as abdominal pain, myalgia, weakness, or shortness of breath develop, consult a doctor immediately. As this medication is excreted through the kidneys, regular kidney function tests should be conducted and the medication should be temporarily discontinued if kidney function deteriorates sharply. If iodine contrast is used during radiology tests, the medication should be stopped before and after the tests, and resumed only after confirming kidney function. In the case of impending surgery, the medication should also be discontinued 48 hours prior to the surgery and resumed after kidney function has recovered post-surgery. This medication may cause side effects such as gastrointestinal disturbances, diarrhea, and loss of appetite, and there may be a risk of vitamin B12 deficiency with long-term use, necessitating regular exams. Elderly patients are particularly prone to decreased kidney function, so dose adjustment and regular kidney function monitoring are important. This medication may interact with other drugs, so notify the doctor or pharmacist of any other medications being taken. Alcohol should be avoided during the course of treatment, and the medication should not be used in cases of acute alcohol intoxication. If an overdose occurs, seek proper treatment immediately at a hospital. Finally, this medication has not been proven safe or effective in children, so it is advisable not to use it in this group.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, pseudo-lymphedema, angioedema, cardiac disorders (angina, acute myocardial infarction, unstable angina, cardiac arrest), acute kidney injury, acute cholangitis, acute cholecystitis, cholangitis, gallstones, asthma, shortness of breath, pneumonia, liver dysfunction (jaundice), hepatitis, acute pyelonephritis, sepsis, severe edema, severe and debilitating arthralgia, severe allergic reactions (urticaria, severe swelling), rash

Mild side effects

Nasopharyngitis, hypersensitivity, urticaria, hypoglycemia (when used with sulfonylureas), dysgeusia, cough, decreased appetite, diarrhea, constipation (when used with insulin), nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rash, severe and debilitating arthralgia, increased lipase, increased amylase, angioedema, decreased and deficient vitamin B12, angioedema, pruritus, rash, pseudo-allergic reactions

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it is important to store it at room temperature between 1 to 30 degrees Celsius to maintain its effectiveness. Storing it this way will prevent the medication from deteriorating or losing its efficacy.

Appearance

Bright yellow, double-convex, oval film-coated tablet

Package unit

60 tablets (10 tablets/PTPX6)