Estorin Tablets (Atorvastatin Calcium Trihydrate)

Adult dosage

Start with a dosage of 10 mg once a day, and for patients requiring greater reduction of LDL cholesterol levels, it can be started at 20 mg or 40 mg once a day. The dosage range is 10 to 80 mg once daily. It should be individualized based on treatment goals and patient response, and lipid levels should be analyzed within 2 to 4 weeks after starting therapy to adjust dosage accordingly. The treatment goal is to lower LDL cholesterol levels, so it is recommended to use LDL cholesterol levels for evaluating treatment initiation and response. However, if LDL cholesterol levels cannot be monitored, total cholesterol levels can be used to monitor treatment responses. In patients with homozygous familial hypercholesterolemia, the dosage range is 10 to 80 mg once daily and is administered in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or if such lipid-lowering therapies are unavailable.

Children's dosage

For pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, start with a dosage of 10 mg daily, with a maximum dosage of 20 mg daily. The dosage should be adjusted every 4 weeks or more.

This medicine may cause muscle-related symptoms, so if severe or persistent muscle pain or weakness occurs, consult a doctor immediately. If muscle-related blood test results are abnormally high, discontinuation of the drug may be necessary. Do not take this medicine if you have liver dysfunction or liver disease, and regular liver function tests should be conducted. Women who are pregnant or may become pregnant should not take this medicine and should use appropriate contraception while taking it. Nursing mothers should also avoid this medicine, and caution should be exercised in children as safety and efficacy have not been sufficiently established. This medicine may interact with certain medications, so if you are taking other drugs, you must inform your doctor or pharmacist. There is no specific antidote for overdose, so treatment should be based on symptoms, and regular liver function and muscle-related tests should be conducted. This medicine should be stored out of the reach of children and kept in its original container to ensure safety. Elderly patients or those with decreased renal function are at higher risk for muscle abnormalities and should take this medicine with greater caution. If symptoms such as skin rash, itching, or blistering appear while taking this medicine, discontinue use immediately and consult a doctor.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, pain in mouth/eye mucosa, severe skin abnormal reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice(yellowing of the skin or eyes), extreme lethargy, liver abnormalities (jaundice), sudden

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• rhinopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medicine may be sensitive to air or moisture, so it should be stored in a closed container. The recommended storage temperature is room temperature between 1 degree and 30 degrees Celsius. This will help safely maintain the medicine's efficacy.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle