Medication info

Aloxid 480 mg (R-Alpha-Lipoic Acid Ammonium Salt)

Prescription medicationApproval withdrawn
Ingredient · strength
R-Thioctic Acid Tromethamine›Strength being verified
Manufacturer / importer
Dae Hwa Pharmaceutical Co., Ltd.
Appearance
Light green, rectangular film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 201904812 · Approved 2019.07.18

This product's status changed to Approval withdrawn on 2023.06.08. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of diabetic polyneuropathy
Who uses it
Adults
Adult dosage
Adults: Take 480 milligrams of thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Ingredients

Manufacturer
Dae Hwa Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of diabetic polyneuropathy

  • Diabetic polyneuropathy
View approved original text

This medication helps alleviate symptoms caused by diabetic polyneuropathy. It reduces pain and numbness resulting from nerve damage, improving the quality of life for patients. With steady use, it may positively influence the recovery of nerve function. Therefore, this drug is used in the treatment of diabetic polyneuropathy.

Dosage and Administration

Adult dosage

Adults: Take 480 milligrams of thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Precautions

This medication contains R-Alpha-Lipoic Acid Ammonium Salt, and individuals allergic to this ingredient, thioctic acid, or other excipients in the medication should not take it. When taking this drug, various adverse reactions may occur. For example, sensory abnormalities, pain, headaches, constipation, abdominal discomfort, dry mouth, and cough have been reported. In severe cases, significant side effects such as nephrolithiasis may occur rarely, so caution is advised. Furthermore, this drug is often used for patients with diabetic neuropathy; those who consume alcohol frequently are at risk of exacerbating nerve symptoms, so it is advisable to avoid alcohol as much as possible. This applies not only during medication but also during the withdrawal period. This drug can form insoluble substances in the body when taken with medications containing certain metal components or milk, so it is recommended not to take it together with iron or magnesium preparations or foods high in calcium. If this medication is taken 30 minutes before breakfast, iron or magnesium preparations should be taken separately at lunch or dinner. Additionally, when taken concurrently with insulin or other diabetes medications, blood sugar levels may drop too low, so blood sugar levels should be monitored frequently, and if necessary, the dosage of diabetes medications should be adjusted. Women who are pregnant or breastfeeding must consult a doctor before taking this medication, and it is safer not to administer it to children under 18 years due to a lack of experience with its use. In the case of overdose, severe intoxication symptoms may occur, so it is essential to go to the hospital immediately for proper treatment. This medication should not be stored at temperatures above 30 degrees Celsius and should be kept in a secure location out of the reach of children and it is advisable not to transfer it to other containers.

Side effects

  • Paresthesia
  • pain
  • sensory loss
  • headache
  • constipation
  • abdominal discomfort
  • nasopharyngitis
  • dry mouth
  • cough
  • cystitis
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  • diarrhea
  • burning sensation
  • nephrolithiasis
  • lumbar spinal stenosis
  • facial swelling
  • dry mouth
  • myalgia
  • nausea
  • decreased appetite
  • arthralgia
  • palpitations
  • insomnia
  • upper limb fracture
  • hypoglycemia
  • neurogenic bladder
  • diabetic retinopathy
  • colitis
  • benign gastric neoplasm
  • gastrointestinal bleeding
  • exacerbation of disease
  • soft tissue infection
  • cold
  • body pain
  • plantar fasciitis
  • herniated disc
  • thyroiditis
  • increased LDH
  • increased triglycerides
  • weight loss
  • abnormal blood sugar
  • shingles
  • dysuria
  • exacerbation of renal dysfunction
  • vaginitis
  • conjunctivitis
  • floaters
  • unspecified retinal vascular disorder
  • heart palpitations
  • acute abdominal symptoms
  • colonic polyp
  • benign oral neoplasm
  • benign gastrointestinal neoplasm
  • gastroesophageal reflux disease
  • gastritis
  • gastroenteritis
  • cavities
  • periodontitis
  • anal bleeding
  • chest pain
  • peripheral edema
  • edema
  • limb pain
  • carpal tunnel syndrome
  • flank pain
  • generalized edema
  • general weakness
  • back pain
  • sleep disorder
  • simple partial seizures
  • facial paralysis
  • bitter taste
  • genital pruritus
  • changes in nails
  • vesicles
  • dermatitis
  • unspecified peripheral vascular disease
  • gum bleeding
  • sputum disorder
  • bronchitis
  • throat infection
  • sinusitis
  • congestion
  • upper respiratory infection
  • allergic atopic rhinitis
  • dyspnea
  • nausea
  • vomiting
  • gastrointestinal pain
  • skin rash
  • urticaria
  • itching
  • dizziness
  • sweating
  • taste disturbance
  • upper abdominal pain
  • dyspepsia
  • itching sensation
  • abdominal pain
  • heartburn
  • generalized convulsions
  • lactic acidosis
  • hypoglycemia
  • shock
  • rhabdomyolysis
  • hemolysis
  • disseminated intravascular coagulation
  • bone marrow suppression
  • multiple organ failure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. This will help preserve the medication's effectiveness over time.

Appearance and packaging

Appearance

Light green, rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.