Olmesartan Medoxomil 10 mg Tablet

Adult dose

The recommended starting dose is 10 mg once daily, administered without regard to meals. If blood pressure is not adequately controlled, the dose may be increased to 20 mg once daily. For additional blood pressure reduction, the dose may be increased up to a maximum of 40 mg once daily. Blood pressure-lowering effects will be evident within 2 weeks after starting treatment, with maximum effects occurring around 8 weeks. If blood pressure is not controlled with monotherapy, it can be combined with thiazide diuretics such as hydrochlorothiazide. To improve adherence, it is advised to take it at the same time each day (e.g., in the morning). In patients with conditions that may lead to reduced intravascular volume depletion (e.g., those on diuretics, particularly those with renal impairment), therapy should begin at a lower dose while closely monitoring their condition.

Child dose

Safety and efficacy in children have not been established.

This medication can cause severe harm or death to the fetus and newborn if taken in the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be used in patients with allergies to this drug or its components, pregnant or breastfeeding women, patients undergoing kidney dialysis, patients with severe liver dysfunction, patients with biliary obstruction, patients with lactose intolerance, particular diabetic patients, and others as indicated. Patients with reduced blood volume or sodium may experience symptoms of hypotension, so their condition should be closely monitored before administration, and appropriate measures should be taken if necessary. In patients with severe heart failure who are dependent on kidney function, changes in kidney function may occur, so caution is needed. Patients with poor kidney function or kidney transplant recipients should frequently check their kidney function and electrolyte status through blood tests, and it's advisable not to use it in patients with severe kidney impairment. In patients with certain renovascular hypertension, worsening of kidney function may occur, so caution is required. This medication may increase potassium levels in the body, so patients with heart or kidney diseases should regularly check their potassium levels. Patients with aortic or mitral valve stenosis and obstructive heart disease should be cautious as symptoms may worsen due to the blood pressure-lowering effect of this medication. It may be ineffective in patients with specific hormonal abnormalities. This medication can lower blood pressure, potentially causing dizziness, so care should be taken when performing potentially dangerous activities like operating machinery or driving. This medication may produce a somewhat lesser blood pressure-lowering effect in Black patients compared to patients of other races. Side effects of this medication are usually mild and transient, potentially including dizziness, headache, dyspepsia, muscle pain, and rash. Facial swelling or angioedema can occur infrequently, so if symptoms appear, immediate consultation with healthcare professionals is advised. Liver function abnormalities or changes in blood test results have been reported uncommonly, so liver function tests may be necessary. If symptoms of weight loss and chronic diarrhea occur during long-term use of this medication, it should be discontinued and a physician consulted. When taking this medication with other blood pressure medications, potassium-sparing diuretics, or potassium supplements, caution is needed as it may increase blood potassium levels. In combination with lithium preparations, there is a risk of lithium toxicity, so concurrent use is not recommended. When used with non-steroidal anti-inflammatory drugs, there is a risk of worsening kidney function, so fluid intake and kidney function monitoring are necessary. Pregnant women should avoid taking this medication due to the risk of severe fetal harm, and it should be discontinued immediately if pregnancy is confirmed. Breastfeeding women should either discontinue breastfeeding or this medication as it may be excreted in breast milk. Safety in children has not been established, so caution is advised in use. Elderly patients may require dosage adjustments and monitoring as drug concentrations may be higher in their bodies. In case of overdose, symptoms such as hypotension and palpitations may occur, and if symptoms arise, immediate consultation with healthcare professionals is necessary. There have been no major risks reported regarding carcinogenicity or genotoxicity; however, regular check-ups are necessary to confirm safety, even with long-term use.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/conjunctival mucosal pain, shortness of breath or breathing difficulty, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision abnormalities, paralysis, numbness

Mild side effects

• Dizziness
• headache
• palpitations
• low back pain
• bronchitis
• diarrhea
• hyperglycemia
• flu-like symptoms
• pharyngitis
• rhinitis

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be kept between 1°C and 25°C at room temperature. This helps maintain the drug's effectiveness and safety over time.

Appearance

White, round, film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle