Medication info
Frezole SR Capsule 100mg (Cilostazol)

Frezole SR Capsule 100mg (Cilostazol)

Prescription medicationHard capsule경구
Ingredient · strength
Cilostazol›100mg / 1 capsule
Manufacturer / importer
대우제약(주)
Appearance
A hard capsule that is white or light yellow and contains granules.
Packaging
30 capsules/bottle, 500 capsules/bottle
Approval status
Active

MFDS item code 201904624 · Approved 2019.07.08 · Insurance code 649605180

Summary

Main use
Improvement of chronic arterial occlusion (ulcers, pain, etc.) and prevention of recurrence of cerebral infarction.
Who takes it
Adults
Adult dose
As cilostazol, the usual adult dosage is 200mg orally once a day. This medication should be taken on an empty stomach, avoiding meals.

Ingredients

Manufacturer
대우제약(주)

Efficacy & effects

Improvement of chronic arterial occlusion (ulcers, pain, etc.) and prevention of recurrence of cerebral infarction.

  • Chronic arterial occlusion
  • ulcers
  • pain
  • cold sensations
  • cerebral infarction
View approved original text

This medication is used to improve ischemic symptoms such as ulcers, pain, and cold sensations caused by chronic arterial occlusion, such as Buerger's disease, obstructive atherosclerosis, and diabetic peripheral vascular disease. It also helps prevent recurrence after a cerebral infarction, especially in cases excluding cardiogenic cerebral embolism, thereby aiding in maintaining brain health. Therefore, it is effective in reducing discomfort due to vascular-related issues and improving healthy blood circulation.

How to take

Adult dose

As cilostazol, the usual adult dosage is 200mg orally once a day. This medication should be taken on an empty stomach, avoiding meals.

Precautions

This medication may increase heart rate, which can lead to angina-like symptoms such as chest pain; hence, careful observation for angina symptoms is necessary. Patients with a high risk of bleeding or a history of bleeding should not use this medication, nor should those with heart failure. Patients who have had allergic reactions to this medication or its ingredients, pregnant women or those who may become pregnant, and nursing mothers should not use this medication. When taken with anticoagulants, antiplatelet agents, thrombolytic agents, etc., the risk of bleeding may increase, so coagulation status should be closely monitored. Women who are menstruating, patients with heart disease, and those with severe kidney or liver dysfunction should also use this medication cautiously. Diabetic patients may be at higher risk for bleeding side effects and should take precautions. Patients with high blood pressure or heart rhythm abnormalities should consult a doctor before using this medication. This medication may cause side effects such as headaches, diarrhea, palpitations, and joint pain, and in severe cases, bleeding, decreased blood cells, pneumonia, and heart problems may occur. Dizziness may occur while using this medication, so care should be taken when driving or operating machinery. Taking this medication with food may increase its blood concentration and the risk of side effects, so it is best to take it on an empty stomach. This medication is metabolized in the liver and kidneys, so dosage adjustment may be necessary for patients with liver or kidney dysfunction. Pregnant or nursing women should not use this medication, and safety in children or newborns has not been established. The elderly should adjust the dosage or use it cautiously due to declining bodily functions. In cases of overdose, severe headaches, diarrhea, low blood pressure, and rapid heart rate may occur, requiring immediate medical attention. This medication may interact with other drugs, so if taking other medications, it is essential to inform a physician or pharmacist.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • angina
  • cerebral hemorrhage
  • headache
  • nausea
  • vomiting
  • altered consciousness
  • hemiplegia
  • pulmonary hemorrhage
  • subcutaneous hemorrhage
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  • gastrointestinal bleeding
  • nasal bleeding
  • retinal hemorrhage
  • hematuria
  • pancytopenia
  • agranulocytosis
  • thrombocytopenia
  • leukopenia
  • aplastic anemia
  • fever
  • cough
  • respiratory distress
  • jaundice
  • elevated AST
  • elevated ALT
  • elevated ALP
  • elevated LDH
  • congestive heart failure
  • myocardial infarction
  • ventricular tachycardia
  • hypoglycemia
  • syncope
  • large cell lung cancer
  • esophageal cancer

Mild side effects

  • Headache
  • diarrhea
  • palpitations
  • joint swelling
  • limb pain
  • chest discomfort
  • phototoxic reaction
  • rash
  • itching
  • back pain
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  • infection
  • chills
  • malaise
  • neck stiffness
  • pelvic pain
  • retroperitoneal hemorrhage
  • atrial flutter
  • loss of tachycardia
  • ventricular tachycardia
  • loss of ectopic contraction
  • ventricular ectopic contraction
  • low blood pressure
  • orthostatic hypotension
  • heart palpitations
  • tachycardia
  • flushing
  • elevated blood pressure
  • anxiety
  • neuralgia
  • weakness
  • strange dreams
  • heaviness in head
  • dizziness
  • insomnia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, avoid storing the medication in excessively hot or cold places, and it is advisable to keep it at room temperature between 1 degree and 30 degrees.

Appearance and packaging

Appearance

A hard capsule that is white or light yellow and contains granules.

Package unit

30 capsules/bottle, 500 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.