Lowstar Tablet 40/10 mg

Adult dose

Take one tablet once daily with water, regardless of meals. It is recommended to take it at the same time every day if possible. Patients with renal impairment should start at a lower dose in severe cases and gradually increase the dose. The elderly should also begin with a lower dose and gradually increase.

Child dose

Safety and efficacy for pediatric patients under 18 years of age have not been established; therefore, use of this drug is not recommended.

This drug may pose serious risks to the fetus and neonate, particularly during the second and third trimesters of pregnancy, and must be discontinued immediately upon confirmation of pregnancy. This drug is contraindicated in patients with certain conditions. For example, individuals who are allergic to this drug, pregnant or potentially pregnant women, nursing mothers, patients with severe liver or heart problems, and those with severe hypotension should not use it. Careful use under the guidance of a physician is necessary for patients with impaired liver function, gastrointestinal disorders, renal issues, and the elderly. While taking this drug, side effects such as dizziness or peripheral edema may occur, and severe side effects have been reported in rare cases, so immediate consultation with healthcare professionals is necessary if unusual symptoms arise. Pregnant women or those planning to become pregnant are advised to replace this drug with other antihypertensives that have established safety, as using this drug during pregnancy may lead to decreased renal function or skeletal formation abnormalities in the fetus. As this drug lowers blood pressure, hypotensive symptoms may occur, and particularly in patients who are deficient in fluids or salts, pre-existing conditions should be improved or the dosage adjusted under medical supervision. There is a risk of elevated potassium levels in the blood, so patients at risk of hyperkalemia should have their blood potassium levels regularly checked, and caution is needed when taking potassium supplements or drugs containing potassium concurrently. Patients with impaired renal function may experience deterioration of kidney function while taking this drug; therefore, kidney status should be monitored regularly through blood tests. Patients with heart disease should be cautious while taking this drug, as it may increase the risk of angina or myocardial infarction, and they should be attentive to any changes in symptoms. This drug may cause drowsiness or dizziness; thus, caution is advised when driving or operating dangerous machinery. Interactions with other medications may occur, so patients should inform their healthcare providers of any current medications, particularly when taken with lithium, digoxin, warfarin, or non-steroidal anti-inflammatory drugs. In the event of overdose, symptoms such as hypotension, dizziness, and irregular heartbeat may appear, necessitating immediate medical attention. This drug has not been proven safe and effective for children, so its use in this population is not recommended. Store this drug out of reach of children and take it immediately after opening; do not transfer it into another container for safety.

Serious side effects

• Hives
• severe swelling (angioedema)
• difficulty breathing (dyspnea)
• jaundice
• sudden and severe headache
• seizures
• confusion
• visual disturbances
• paralysis
• significantly reduced urine output

Mild side effects

• Dizziness
• peripheral edema
• upper respiratory infection
• urinary tract infection
• anemia
• hyperkalemia
• depression
• insomnia
• headache
• drowsiness

This drug is sensitive to light, so it should be stored in a container that does not allow light to pass through. Additionally, it is recommended to store the medication at room temperature between 1°C and 30°C to maintain its efficacy.

Appearance

The tablet is a biconvex oval-shaped double-layer tablet that is white and light gray.

Package unit

30 tablets/PVP [(10 tablets/PTPX3)]