Albekem Tablets

Adult dose

Typically taken orally, 2 tablets twice a day before breakfast and bedtime, regardless of meals. 1) Gastric and duodenal ulcers: Administer 2 tablets twice daily or 4 tablets once a day at bedtime. Particularly for patients with duodenal ulcers, administering 4 tablets twice daily before breakfast and bedtime can achieve a higher treatment rate. The dosage is the same for prophylactic combination therapy for ulcers caused by NSAIDs or long-term administration of NSAIDs usually heals within 8 weeks for diseases caused by NSAID use within 4 weeks, but healing periods may be extended depending on the patient. For patients with recurrent ulcers who had excellent results with short-term therapy with this medication, maintenance therapy of 2 tablets once nightly may be administered. 2) Gastroesophageal reflux disease: Administer 2 tablets twice daily for 8 weeks or 4 tablets once daily at bedtime. In severe cases of gastroesophageal reflux disease, the dosage may be increased to 4 tablets four times daily. 3) Zollinger-Ellison syndrome: Start treatment with an initial dose of 2 tablets three times daily, and increase the dose as necessary. In severe cases, up to 6 g of ranitidine may be administered daily as directed by a physician. 4) Peptic ulcers, acute stress ulcers, and upper gastrointestinal bleeding due to acute mucosal lesions: Once oral administration is possible, transition from injection to oral administration and administer 2 tablets twice daily. 5) Pre-anesthesia administration (prevention of Mendelson's syndrome): Administer 2 tablets 2 hours before induction of anesthesia. It is also advisable to administer 2 tablets on the night before surgery.

This medication should not be administered to patients with poor kidney function or those undergoing dialysis. Patients who have had allergic reactions to this drug or its components should also avoid it. Patients with a history of acute porphyria should not be given this drug, as it may exacerbate symptoms. Patients who have undergone gastrointestinal surgery or those who need to limit potassium intake should not use this medication for safety. It should not be given to pregnant women or those who may become pregnant, nor to premature infants or newborns. Patients with liver dysfunction or a history of drug allergies should use this medication cautiously, and elderly patients and those with a history of kidney disease need to be careful. If taking non-steroidal anti-inflammatory drugs (NSAIDs) together, especially elderly individuals or those with a history of peptic ulcers should undergo regular monitoring during treatment. Because it may mask symptoms of stomach cancer, patients with gastric ulcers or those over middle age with new or changed symptoms of dyspepsia should verify the absence of malignant diseases before use. Patients with Helicobacter pylori infection and gastric or duodenal ulcers should receive concomitant treatment to eradicate the bacteria. Use in severe critical care patients may lead to gastric stones, and caution is needed for patients with hypophosphatemia as the aluminum component of this drug may interfere with phosphate absorption. Care should be taken for patients who have difficulty swallowing as there is a risk of respiratory complications. Rarely, shock or severe allergic reactions may occur when taking this medication, so if symptoms appear, treatment should be stopped immediately and medical assistance sought. Allergic symptoms may include skin rash, urticaria, angioedema, fever, and bronchospasm, and all medications should be discontinued if such symptoms develop. Abnormalities may appear in blood tests, and if symptoms such as fatigue, bleeding, or fever arise, immediate testing and necessary measures should be taken. If symptoms of liver dysfunction occur, the medication should be discontinued immediately, as cardiac-related abnormalities such as arrhythmia or vasculitis have also been reported rarely. Gastrointestinal symptoms may include nausea, vomiting, constipation, diarrhea, and abdominal pain, and stool color may change, although this does not require treatment. Severe cases, particularly in the elderly, may exhibit neurological symptoms such as dizziness, drowsiness, confusion, seizures, insomnia, headaches, anxiety, etc., so careful observation is required. Musculoskeletal symptoms such as myalgia or arthralgia may also occur rarely, and in severe cases, discontinuation of the medication is required. Symptoms such as skin itching, hair loss, or stomatitis may also occur. Avoid long-term use, and if no therapeutic effect is observed, switch to another medication while regularly testing blood, liver, and kidney functions. Elderly or chronically ill patients may have an increased risk of pneumonia, requiring caution. If dizziness or drowsiness occurs while taking this medication, avoid driving or operating hazardous machinery. There may be interactions with other medications, so inform your doctor or pharmacist of any medications being taken, as some may require dosage adjustments or discontinuation when taken with this medication. It is safest for women who are pregnant or breastfeeding to avoid taking this medication. Safety in children has not been established, so it is recommended not to administer this medication to children. In case of overdose, emergency measures such as vomiting or gastric lavage may be necessary, and blood dialysis may be performed if needed. This medication may reduce gastric acid secretion and promote bacterial growth within the gastrointestinal tract, so ophthalmic examinations may be needed with long-term use.

Serious side effects

• Urticaria
• severe swelling (angioedema)
• tightness in the chest
• difficulty breathing
• shock
• anaphylactic shock
• angioedema
• severe allergic reactions
• severe rash with high fever
• blisters

Mild side effects

• Skin rash
• angioedema
• fever
• bronchospasm
• hypotension
• chest pain
• granulocytopenia
• leukopenia
• thrombocytopenia
• elevation of serum enzyme levels

This medication should be stored in a sealed container to prevent air exposure, and the storage temperature should be maintained between 1°C and 30°C. Proper storage will help maintain the effectiveness of the medication.

Appearance

Green round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle