Limaclemone Tablet (Limaprost Alpha-Dex)

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness associated with thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability associated with acquired lumbar spinal canal stenosis (in patients with a normal straight leg raise [SLR] test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose appropriately according to age and symptoms.

This medication should not be used in women who are pregnant or may become pregnant. This medication contains lactose; therefore, it should not be administered to patients with genetic disorders that impair lactose digestion. Caution should be exercised in patients with a tendency to bleed or those taking anticoagulant medications. If allergic reactions such as skin rash or itching occur while using this medication, use should be discontinued immediately. Since bleeding can occur rarely, if there are symptoms of bleeding, stop the medication and consult a physician. Gastrointestinal symptoms such as diarrhea, nausea, and abdominal discomfort may occur, so caution is needed. Liver function abnormalities may occur, so the condition of liver health should be monitored. Symptoms such as rapid heartbeat or low blood pressure may occur. Headache, facial flushing, dizziness, and tremors may occur, so any unusual symptoms should be reported. Patients with lumbar spinal stenosis should observe changes in symptoms and decide whether to continue medication. Safety during pregnancy has not been established, and uterine contraction effects have been reported in animal studies, so it should not be administered to pregnant women. Safety in children has not been confirmed, as there is no experience of use. Elderly patients may have decreased physiological functions, so caution is necessary in adjusting the dosage of the medication. Healthy adults should be cautious, as large doses can temporarily lower blood pressure.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication should be stored in a tightly closed container to keep it dry and protected from air or moisture. It is best to store the medication at room temperature between 1°C and 30°C. By storing it like this, the effectiveness of the medication can be safely maintained.

Appearance

White round tablets

Package unit

84 tablets/box [(21 tablets/Alu-Alu X4)]