Rosuvastatin 20mg Tablets (Rosuvastatin Calcium)

Adult dosage

For conditions such as primary hypercholesterolemia, this medication is initiated at a dose of 5 milligrams once daily and adjusted as needed up to 10 milligrams at intervals of 4 weeks or more. The maintenance dose is primarily 10 milligrams once daily, and the maximum dose is 20 milligrams once daily. It can be administered at any time during the day regardless of meals.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosage is administered once daily in the range of 5 milligrams to 20 milligrams. The dosage should be adjusted according to individual patient needs with a minimum interval of 4 weeks.

This drug should not be administered to certain patients. First, individuals allergic to any components of this drug should not take it. Patients with active liver disease or those with abnormally elevated liver enzyme levels in blood tests should also avoid this drug. Patients with muscle diseases or those taking the immunosuppressant cyclosporine should refrain from using this medication. Patients with severe renal impairment, women who are pregnant or breastfeeding, and fertile women who do not use appropriate contraception also should not use this medication. In particular, high dosing is prohibited in patients at greater risk of muscle disease. In addition, patients with genetic disorders related to lactose intolerance should avoid this medication. This drug may affect liver function; therefore, patients with a history of liver disease or those who consume alcohol excessively should undergo regular liver function tests. Symptoms such as muscle pain or weakness should be reported to healthcare providers immediately, and if necessary, blood tests should be conducted to check for muscle damage. Patients at high risk for severe muscle diseases require careful observation and testing before and after taking this medication. In cases of acute illness or severe conditions, this medication should be discontinued, and if severe muscle weakness occurs, it should be stopped immediately. This medication may interact with other drugs; therefore, it is essential to inform healthcare providers about any co-administered medications. Caution is advised when used with drugs that may increase the risk of muscle disease, and some drugs should be avoided in combination. This drug should not be used during pregnancy or breastfeeding, and women of childbearing potential should use appropriate contraception. There are no specific antidotes for overdose, so treatment should be symptomatic, and liver function and muscle enzyme tests are required. This medication may cause side effects such as dizziness, so caution is needed when driving or operating machinery. Finally, it is crucial to regularly check liver and muscle health status while on this medication and to consult healthcare providers immediately if any abnormal symptoms occur.

Serious side effects

Allergic reactions including urticaria and angioedema, severe muscle weakness, ocular muscle weakness, rhabdomyolysis, severe allergic reactions, severe skin adverse reactions (Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms DRESS), jaundice, hepatitis, acute renal failure, oliguria, severe edema, chest tightness, shortness of breath, respiratory distress, asthma attacks, fatal and non-fatal liver failure, serious

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• diarrhea

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. The storage temperature should be kept between 1 to 30 degrees Celsius, and it is advisable to keep it in a cool place away from direct sunlight.

Appearance

Pink circular film-coated tablets

Package unit

PTP - 28 tablets/PTP [(14 tablets/PTP x 2)]