Banzelis Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

The tablet should be swallowed whole with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, an additional 4 weeks is recommended. - Maintenance therapy to prevent recurrence: 20 mg once daily. - Treatment of symptoms without esophagitis: 20 mg once daily. After symptom relief,

Children's dosage

Adolescents aged 12 and older - Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, an additional 4 weeks of treatment may be necessary. - Treatment of symptoms without esophagitis

This medication should not be administered to certain patients. Patients with a known allergy to this medication or its components, or with a history of hypersensitivity to benzimidazoles, should not take it. Patients with hypersensitivity to antibiotics such as amoxicillin or clarithromycin when undergoing Helicobacter pylori eradication therapy should exercise caution. Additionally, it is advisable for patients taking certain heart-related medications or antivirals, those with a history of myocardial infarction, and nursing women to avoid using this medication. Various adverse reactions may occur during treatment, with common symptoms reported including headache, abdominal pain, diarrhea, and dizziness. Rarely, blood abnormalities, liver function abnormalities, skin rashes, myalgia, and neurological symptoms may occur, and if any symptoms are severe or persist, immediate consultation with healthcare providers is advised. Particularly with prolonged use, electrolyte imbalances such as hypomagnesemia can occur, necessitating regular blood tests. Moreover, this medication suppresses gastric acid secretion, which may increase the risk of bacterial overgrowth in the gastrointestinal tract, so patients should inform their healthcare provider if diarrhea persists for an extended period. This medication has a high potential for interactions with other drugs, especially when used in combination with anticoagulants, anticonvulsants, antidepressants, and antivirals, so caution is advised. Data on safety during pregnancy is limited, so pregnant women should only take this medication after consulting with their doctor, and it is recommended that breastfeeding women do not take this medication. In case of overdose, there is no specific antidote, and symptomatic treatment based on the symptoms is necessary, and it is important to keep this medication out of the reach of children.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, shock, fever, angioedema, anaphylactic reactions, agranulocytosis, pancytopenia, hyponatremia, hypomagnesemia, hepatitis, liver failure, jaundice, skin and mucosal adverse reactions (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, Clostridium difficile

Mild side effects

Headache, insomnia, agitation, confusion, depression, aggression, hallucinations, dizziness, drowsiness, taste disturbances, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, asthenia, increased sweating, Clostridium difficile-associated diarrhea, facial swelling, facial flushing,

This medication may be sensitive to air and moisture; therefore, it is important to store it in a tightly closed container. Additionally, it should be stored at room temperature, between 1 to 30 degrees Celsius, avoiding excessively hot or cold locations. This will help maintain the drug's efficacy and safety.

Appearance

Pink circular film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu*2)