Light H Co., Ltd. (Pre-filled) (Sodium Hyaluronate)

Adult dosage

As sodium hyaluronate, 25mg is injected into the intra-articular space of the knee or shoulder (shoulder joint space, subacromial bursa, or biceps tendon sheath) once a week for 5 weeks, adjusting the number of doses according to symptoms. This medication is administered into the knee joint under strict aseptic conditions.

This medication contains sodium hyaluronate and is injected into the joint to assist in lubrication. This medication should not be used in individuals with a history of hypersensitivity or those with skin diseases or infections at the injection site. Individuals with liver function issues or a history of liver disorders should use this medication cautiously, as abnormal results may appear in liver function tests. It is also safe to avoid this medication in individuals allergic to avian proteins. Shock or allergic reactions may occur during administration, so if unusual symptoms appear, use should be immediately stopped and appropriate treatment should be sought. Temporary pain, swelling, redness, and heat may occur at the injection site, and rarely, skin rashes or itching may develop. If there is severe inflammation in the joint before administration, it is advisable to alleviate the inflammation first. After administration, the joint area should be stabilized, and care should be taken to prevent the medication from leaking out of the joint. Patients with rheumatoid arthritis or gouty arthritis may require monitoring as inflammation may temporarily worsen. It is advisable to avoid vigorous exercise or prolonged weight-bearing activities within 48 hours post-injection. The safety and efficacy of using this medication together with other intra-articular injectables have not been confirmed, so co-administration should be avoided. For pregnant women or those who may become pregnant, the administration of this medication should be carefully considered, and it is recommended to avoid use during breastfeeding. The safety in children has not been established, so use should be cautious and only when necessary. Elderly patients may have decreased bodily functions, so special caution should be taken. Maintain a sterile condition during injection, and it must be injected accurately into the joint cavity; intravascular injection is strictly prohibited. A needle of appropriate gauge that matches the characteristics of the viscous medication should be used, and the medication should be slowly drawn into the syringe. Shake the ampoule to ensure proper mixing of the medication, and use it immediately after opening, discarding any remaining medication.

Serious side effects

• Hives
• Severe swelling (edema)
• → Severe allergic reaction
• Shock
• → Severe allergic reaction

Mild side effects

Swelling (facial, eyelid, etc.), facial flushing, rash, itching, pain (mainly transient pain after administration), enlargement, edema, redness, heat, localized severe pressure sensation, petechiae, nausea, vomiting, fever, headache

Pre-filled syringes are contained in sealed containers and must be stored at a temperature between 1 degree and 30 degrees Celsius to maintain medication efficacy and safety.

Appearance

A colorless, transparent, viscous solution contained in a glass tube sealed with rubber stoppers (part of the pre-filled syringe system)

Package unit

10 pre-filled syringes/box [2.5 milliliters/pre-filled syringe], 50 pre-filled syringes/box [2.5 milliliters/pre-filled syringe], 100 pre-filled syringes/box [2.5 milliliters/pre-filled syringe]