Esamlodipine 2.5 mg Tablet (S-Amlodipine Besylate Hydrate)

Adult dose

Take this medication with a sufficient amount of water. Administer 2.5 mg orally once daily as S-Amlodipine, and the dosage may be increased to a maximum of 5 mg per day depending on the patient's response. Adjust dosage appropriately according to symptoms.

This medication should not be administered to certain patients. For example, it should not be used in patients who have an allergy to this medication or its components, or who have had hypersensitivity reactions to similar types of medications. Additionally, women who are pregnant or may become pregnant, or those who are breastfeeding should not use this medication. Patients with cardiogenic shock, severe aortic stenosis, unstable angina, within 1 month post-myocardial infarction, severe liver function impairment, or hypotension should also avoid taking this medication. This medication contains lactose, thus it should not be given to patients with lactose intolerance or related genetic disorders. Caution should be exercised when used in patients with severe renal impairment, the elderly, those with acute heart failure, hypertensive crisis, and patients with mild to moderate liver dysfunction. Although this medication generally has good tolerability, side effects such as warmth or flushing, fatigue, edema, palpitations, dizziness, headache, abdominal pain, nausea, drowsiness, and ankle edema may occur. Rarely, hypotension, vasculitis, skin rash, liver dysfunction, and allergic reactions may occur; if any unusual symptoms appear, consult a physician immediately. Sudden discontinuation of this medication may worsen symptoms, so the dosage should be reduced gradually under medical supervision. Special attention is needed for patients with heart failure or liver dysfunction, and it is advisable to take this medication with adequate fluids. Dizziness or fatigue may occur due to blood pressure reduction; caution is advised when driving or operating hazardous machinery. Drug interactions may occur when combined with other medications, so patients should inform healthcare providers about any current medications. It is particularly advised to avoid taking this medication with grapefruit juice as it may increase the hypotensive effect. Use of this medication is not recommended when pregnant or breastfeeding due to lack of established safety. It is only to be used in children over 6 years of age, and elderly patients should start at a low dose and be monitored closely. In cases of overdose, severe hypotension, arrhythmias, and shock may occur, requiring immediate medical attention; blood dialysis is ineffective. This medication should be kept out of reach of children and should not be transferred to other containers to ensure safety.

Serious side effects

Urticaria, angioedema, severe swelling (edema), difficulty breathing, chest tightness, toxic epidermal necrolysis, jaundice, hepatitis, sudden and very severe headache, paralysis, seizures, confusion, vision changes, significantly reduced urine output, severe edema associated with elevated blood pressure

Mild side effects

Flushing with warmth, fatigue, edema, palpitations, dizziness, headache, migraine, weakness, abdominal pain, nausea, dyspepsia, drowsiness, dry mouth, increased sweating, weakness, lethargy, pain, weight gain/loss, chills, hypotension, orthostatic hypotension, postural dizziness, peripheral ischemia, vasculitis, syncope, tachycardia, peripheral edema, tension, sensory disturbances/sensory abnormalities, peripheral neuropathy, taste distortion, tremors, extrapyramidal symptoms, erectile dysfunction, gynecomastia

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees at room temperature to safely preserve the medication's effectiveness.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle