Rosatol Plus Tablet

Adult dosage

The usual dosage of this medication is one tablet containing 50 mg of Losartan Potassium and 12.5 mg of Hydrochlorothiazide once daily. Doses exceeding 100 mg of Losartan Potassium and 25 mg of Hydrochlorothiazide daily are not preferable. Start with one tablet of 50 mg of Losartan Potassium and 12.5 mg of Hydrochlorothiazide once daily; if blood pressure is not controlled after 3 weeks, increase to a maximum of 100 mg of Losartan Potassium.

Children's dosage

There is no experience using this medication in children and adolescents; thus the combination of losartan and hydrochlorothiazide is not administered to children and adolescents.

This medication can cause serious harm to the fetus if taken during pregnancy, especially during the second and third trimesters, and should be discontinued immediately upon confirmation of pregnancy. This medication should not be administered to certain patients, for instance, those allergic to this medication or its components, patients with severely impaired kidney function, severe liver impairment, women who are pregnant or may become pregnant, and those with specific electrolyte abnormalities. Additionally, patients with low blood pressure or problems with renal blood vessels, those with a history of liver disease, diabetes or gout, and the elderly should use this medication with caution, and sun exposure should be limited due to an increased risk of skin cancer, while skin condition should be monitored frequently. During the use of this medication, electrolyte imbalances, especially changes in potassium levels, should be carefully monitored, as symptoms of excessively low blood pressure, dizziness, or drowsiness may occur, requiring caution while driving or operating machinery. As this medication may interact with other drugs, especially potassium-sparing diuretics, potassium supplements, non-steroidal anti-inflammatory drugs, and lithium preparations, consultation with a physician is advised if taken in combination. This medication also requires caution in nursing women, and it is necessary to decide whether to discontinue breastfeeding or consult a doctor prior to administration. The safety of this medication in children and adolescents has not been established, thus it is not administered to this age group. If any abnormal symptoms appear during administration, consult a healthcare professional immediately, especially in cases of suspected allergic reactions such as skin rash, difficulty breathing, or severe dizziness; discontinue use immediately.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, angioedema (swelling of lips and eyelids and facial rashes, laryngeal/pharyngeal edema potentially causing airway obstruction), severe allergic reactions, severe cutaneous adverse reactions (severe rash, blisters, skin sloughing, Stevens-Johnson syndrome, toxic epidermal necrolysis), acute respiratory distress syndrome (ARDS), liver

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication should be stored in a tightly closed container that blocks light, and the storage temperature should be maintained between 1 degrees and 30 degrees Celsius at room temperature. By storing it this way, the efficacy of the medication can be safely maintained.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle