Hyalex Plus Injection (Pre-filled) (Sodium Hyaluronate)

Adult dosage

Typically, for adults, 1 injection per week for 3 weeks continuously administered into the knee joint or shoulder joint, but the frequency may be adjusted according to symptoms.

This drug should not be used in patients who have had allergic reactions to any component of this medicine. Patients who have had allergic reactions to other drugs or have liver function problems, or who have a history of liver disease, should use this drug with caution. Additionally, before administering this drug, the condition of the joint injection site should be carefully checked if there are any skin diseases or infections present. Rarely, severe allergic reactions, such as shock, may occur when using this drug, so if symptoms develop, administration should be stopped immediately and appropriate treatment should be administered. If allergic symptoms such as swelling or redness of the face, rash, hives, or itching occur, the use of the drug should be discontinued and medical assistance should be sought. Temporary pain, swelling, redness, warmth, or severe pressure may occur at the injection site, and rest is required if these symptoms are present. Occasionally, symptoms such as nausea, vomiting, or fever may appear, so if symptoms persist, consultation with medical personnel is recommended. In cases of severe joint inflammation, it is advisable to reduce the inflammation first before using this drug, and post-administration, it is recommended to stabilize the injection site. When injecting, aseptic techniques must be maintained, and the injection should be accurately administered into the joint. If symptoms do not improve after three injections, administration should be stopped, and if fluid accumulates in the joint, it is preferable to remove it via puncture before using the drug. This drug should not be used for intravascular administration or for ophthalmic use, and it is recommended to use needles that are around 22-23 gauge. Caution is needed as the drug may precipitate when used with disinfectants. Women who are pregnant or may become pregnant should carefully weigh the benefits and risks when using this drug, and it is advisable to avoid breastfeeding while using this drug. Safety for children has not been established, and it should only be used with caution when absolutely necessary. Elderly patients may have decreased physical function, so extra caution is required when using this drug.

Serious side effects

• Shock symptoms
• hives
• swelling (face, eyelids, etc.).

Mild side effects

• Facial flushing
• itching
• pain
• swelling
• redness
• warmth
• localized severe pressure
• nausea
• vomiting
• fever

This drug should be stored in a sealed container to prevent exposure to air and kept at room temperature between 1°C and 30°C. Proper storage helps maintain the drug's effect and prevents deterioration.

Appearance

A colorless, transparent, and viscous liquid contained in a glass or plastic tube sealed with rubber stoppers at both ends (part of a prefilled syringe system).

Package unit

2 milliliters/cylinder [2ml x 1 tube], 2 milliliters/cylinder [2ml x 3 tubes]