Tianon Tablets (Thianaphtine Sodium)

Adult dose

Administer 12.5 mg of tianeptine sodium per dose orally 3 times daily before meals. Limit the dosage to twice daily in patients aged 70 years and older or in patients with renal impairment. Adjust the dose as appropriate according to symptoms. Avoid abrupt discontinuation of treatment. To reduce the risk of withdrawal reactions, gradually taper the dose over 7 ~ 14 days. (See “General Precautions” in the Precautions for Use section.)

This drug is used in the treatment of depression and may increase the risk of suicidal thoughts or self-harm, so patients should be carefully monitored at the beginning of treatment. Specially, patients with a history of suicide attempts or suicidal thoughts require closer management. This drug should not be used in children under 15 years of age or in patients taking certain medications such as MAO inhibitors, and should be avoided in cases of allergy to the drug's components. During treatment, various side effects such as decreased appetite, insomnia, drowsiness, headache, palpitations, and gastrointestinal disturbances may appear, so consultation with a physician is necessary if there are abnormal symptoms. Patients approaching surgery should inform the anesthesiologist about this medication and are advised to discontinue use 24 to 48 hours prior to surgery. It is recommended not to take this drug with alcohol or medications containing alcohol, and sudden discontinuation can lead to withdrawal symptoms like anxiety, muscle pain, and insomnia, so dosing should be gradually reduced under a doctor's guidance. Caution should be exercised when driving or operating machinery due to risks of drowsiness or decreased concentration, and patients with a history of substance abuse should be particularly careful about overdose. For patients with impaired renal function or the elderly, it may be necessary to limit the frequency of dosing due to prolonged retention of the drug in the body. It is safer for pregnant or breastfeeding women to avoid this medication, and caution is also necessary for elderly patients. In cases of overdose, drowsiness or coma may occur, and immediate medical attention should be sought for appropriate treatment. Keep the drug out of reach of children and store it in its original container for safety.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal thoughts
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This drug should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle