Tralitin Combi Tablet 2.5/500 mg

Adult dose

The dosage of this medication should be determined considering each patient's treatment regimen, efficacy, and tolerability, without exceeding the maximum recommended dosages of linagliptin 2.5 mg and metformin 1000 mg, taken twice daily. This medication is to be administered twice daily with meals. 1. If not currently treated with metformin: The initial dosage is 2.5/500 mg taken twice daily, one tablet per dose and may increase to 2.5/1000 mg taken twice daily, one tablet per dose.

This medication helps to control blood sugar. However, it should not be used in patients with severely impaired kidney function or acute heart disease, or in patients with liver dysfunction. Pregnant or nursing women are also advised not to take this medication. This medication can cause hypoglycemia, so caution should be exercised to monitor blood sugar changes when used in combination with insulin or sulfonylureas. Particularly, the risk of hypoglycemia increases with excessive exercise, insufficient food intake, or alcohol consumption. A rare side effect known as lactic acidosis may occur, which poses a greater risk during sudden deterioration of kidney function, severe infections, or dehydration. In such cases, immediate consultation with a physician and cessation of medication are necessary. Regular blood tests to check kidney function and vitamin B12 levels are important during the use of this medication. Additionally, this medication may cause pancreatitis or blistering skin conditions, so any severe abdominal pain or skin abnormality symptoms should be reported to healthcare professionals immediately. There may be drug interactions; hence, if taking other medications, it is essential to inform the physician or pharmacist, especially when used with medications that affect the kidneys. The safety and efficacy of this medication have not been established in children, and dosage adjustments should be considered for elderly patients due to decreased kidney function. Finally, this medication should be stored out of the reach of children and protected from moisture.

Serious side effects

urticaria, angioedema, lactic acidosis, pancreatitis, similar dermatitis, acute pancreatitis, angioedema, acute myocardial infarction, cardiac arrest, unstable angina, angina pectoris, congestive heart failure, acute kidney injury, hepatitis, acute cholangitis, acute cholecystitis, cholangitis, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin abnormal reactions, shortness of breath or difficulty breathing, asthmatic attacks, cough+

Mild side effects

• nasopharyngitis
• hypersensitivity
• hypoglycemia
• taste disorder
• cough
• appetite loss
• diarrhea
• constipation
• nausea
• vomiting

This medication should be stored in a tightly sealed container to avoid exposure to air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Storing it this way helps to maintain the effectiveness of the medication and prevent degradation.

Appearance

Bright yellow, biconvex, oval-shaped film-coated tablet

Package unit

60 tablets (10 tablets/ PTP X 6)