Glymeperide Tablet 4mg (Glymeperide)

Adult dose

Administer orally once daily. This medication should be taken before breakfast or just before the first meal. For patients who have not previously received treatment, start at 1 mg of glymeperide once daily. If necessary, the dose can be increased by 1 mg at intervals of 1–2 weeks. Generally, once a dose of 4 mg or more is administered, additional effects are minimal; however, some patients have exhibited better metabolic control by increasing the dosage up to 6 mg.

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or coma. Patients allergic to this medication or to sulfonylureas or sulfonamides should also avoid it. There is no experience using this medication in patients with severe liver or kidney dysfunction, so transitioning to insulin therapy is recommended. Women who are pregnant or may become pregnant, and nursing mothers should not take this medication. Insulin therapy is more appropriate for patients with severe infections, pre- or post-surgery, or those with severe trauma. Gastric disturbances such as diarrhea or vomiting can impede food absorption and increase the risk of hypoglycemia. This medication contains lactose and should not be administered to patients with genetic issues such as lactose intolerance or lactase deficiency. In the first week of treatment, there is a high risk of hypoglycemia, so monitoring should be particularly attentive. Elderly individuals, those with malnutrition, irregular meals, skipped meals, excessive exercise, imbalanced carbohydrate intake, or alcohol consumers are at higher risk of hypoglycemia. Patients with kidney or liver dysfunction may also be more sensitive to hypoglycemia, necessitating caution. Extra attention should be paid in cases of other endocrine disorders, overdosing on medications, or taking multiple drugs simultaneously. In such cases, blood sugar levels should be checked frequently, and if hypoglycemic symptoms occur, the physician or pharmacist should be notified immediately. This medication may cause hypoglycemia, and symptoms may include headaches, severe hunger, nausea, fatigue, anxiety, confusion, drowsiness, and decreased consciousness. Severe hypoglycemia may exhibit symptoms similar to a stroke, necessitating immediate treatment. Temporary blurred vision may occur, as well as gastrointestinal disturbances leading to nausea, vomiting, abdominal pain, and diarrhea. Liver dysfunction or blood abnormalities and allergic reactions may occur rarely, so immediate consultation with medical personnel is advised for any unusual symptoms. When taking this medication, regular meals and exercise, along with weight management, are crucial. If hypoglycemia occurs, sugar or sweet drinks should be consumed quickly to raise blood sugar levels, and it is advisable to always carry some sugar. Regular blood sugar and urine tests should be conducted during treatment to monitor the medication's effectiveness. Caution is advised when driving or operating machinery, as hypoglycemia or hyperglycemia may impair concentration. When taking this medication with other drugs, it may affect blood sugar control, so patients must inform their doctor or pharmacist about any medications they are taking. Especially, using drugs that affect the enzymes that break down this medication in the liver may alter its effectiveness. Alcohol consumption can unpredictably alter the blood sugar-lowering effects of this medication. Women who are pregnant or breastfeeding should avoid this medication, as it may affect the fetus or newborn; transitioning to insulin therapy is safer. The safety and efficacy of this medication in children under 18 have not been established, so its use is not recommended. Elderly patients may have reduced kidney function and may require dose adjustments. In cases of overdose, severe hypoglycemia may occur, requiring immediate emergency treatment, and patients must be closely monitored for at least 24-48 hours. This medication should be kept out of reach of children, and it is important to store it sealed in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary issues.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• reduced agility or activity level

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to avoid direct sunlight and to store it at room temperature between 1 to 30 degrees Celsius.

Appearance

Light blue rectangular tablet

Package unit

30 tablets/bottle, 300 tablets/bottle