Celebrex 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Administer celecoxib 200mg once daily, or 100mg per dose in 2 divided doses daily. 2. Rheumatoid arthritis Administer celecoxib 100mg or 200mg per dose twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200mg once daily, or 100mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, a dose of up to 400mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400mg daily, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400mg, with an additional 200mg on the first day of treatment if needed. From the second day of treatment, the recommended dose as needed is 200mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class Ⅱ), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug can pose a risk of gastrointestinal bleeding for those who regularly consume more than three glasses of alcohol daily, so it is essential to consult a doctor or pharmacist. This medication may increase the risk of serious cardiovascular issues such as cardiovascular thrombotic events, myocardial infarction, and stroke, so it should only be used at the minimum effective dose and for the shortest duration possible. In the gastrointestinal tract, serious issues such as ulcers, bleeding, and perforation may occur, thus special caution is warranted for the elderly or those with a history of gastrointestinal disease. This medication may cause allergic reactions; therefore, individuals with hypersensitivity to this drug or similar medications should not take it. Patients with significantly impaired liver or kidney function, active peptic ulcers, or inflammatory bowel diseases should not use this medication. Pregnant women or those who may become pregnant, nursing mothers, and patients with certain cardiovascular diseases should also avoid this medication. Patients with liver or kidney issues or a history of hypertension, heart failure, or asthma should take special caution when using this medication and should follow their doctor’s guidance. While taking this drug, it is crucial to be vigilant for symptoms of gastrointestinal bleeding (epigastric pain, black stools, vomiting blood), cardiovascular symptoms (chest pain, shortness of breath), and allergy-related symptoms. This drug can interact with several other medications, so inform your doctor or pharmacist if you are taking other drugs, particularly antihypertensives, anticoagulants, or antidepressants. Taking this medication during pregnancy may lead to side effects for the fetus, hence women who are pregnant or planning to become pregnant should avoid its use. Elderly patients may have decreased kidney and liver function, necessitating more cautious monitoring when using this drug. Patients using this medication long-term should undergo regular blood tests and liver and kidney function monitoring, and consult healthcare providers immediately if any abnormal symptoms occur. This medication can cause drowsiness or dizziness, making it advisable to avoid driving or operating machinery after taking it. If symptoms such as rashes, mucosal lesions, fever, or itching occur during treatment, discontinue use immediately and consult a physician. In case of overdose, symptoms may include vomiting, drowsiness, and gastrointestinal bleeding, so strictly adhere to the dosage and seek immediate medical attention if symptoms arise.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tone increase, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechial hemorrhage, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute kidney injury, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, decreased appetite, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormality, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fracture, tendon rupture, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechial bleeding, nosebleed, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic granuloma, contact dermatitis, injection site reaction, skin nodules, headache, vertigo, constipation, dry mouth, ulcerative stomatitis, gastritis, allergy, back pain, chest pain, hyperlipidemia, weight gain, fracture, arthralgia, positive RA factor, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss, anaphylactic reaction, hallucinations, intracerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug eruption accompanied by eosinophilia and systemic symptoms, acute generalized pustular psoriasis, exfoliative dermatitis, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, weakness, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, vasculitis, thrombophlebitis, deep vein thrombosis, intracerebral hemorrhage, ventricular fibrillation, syncope

Store this medication in a tightly sealed container to prevent exposure to air and moisture. The safest storage temperature is at room temperature, between 1 and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle