Medication info
Lafustar Tablet 10mg (Lafutidine)

Lafustar Tablet 10mg (Lafutidine)

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Dongkoo Pharmaceutical Co., Ltd.
Appearance
White, round film-coated tablet
Packaging
Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle
Approval status
Active

MFDS item code 201903815 · Approved 2019.06.11 · Insurance code 653404430

Summary

Main use
Treatment of gastrointestinal disorders (such as ulcers and gastritis), preanesthetic medication, and combination therapy for Helicobacter pylori
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is lafutidine 10mg orally once daily at bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may vary among patients. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is lafutidine 10mg orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg orally twice daily.

Ingredients

Manufacturer
Dongkoo Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (such as ulcers and gastritis), preanesthetic medication, and combination therapy for Helicobacter pylori

  • Gastric ulcer
  • duodenal ulcer
  • gastric mucosal lesions from acute and chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medication is used for the treatment of gastric and duodenal ulcers. It also improves gastric mucosal damage caused by acute and chronic gastritis, and is effective when used in combination with antibiotics for patients with peptic ulcers caused by Helicobacter pylori infection. It is also utilized for pre-anesthesia administration and is useful for the treatment of gastroesophageal reflux disease. Overall, it is used for treating various gastrointestinal-related diseases and improving symptoms.

How to take

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is lafutidine 10mg orally once daily at bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may vary among patients. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is lafutidine 10mg orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg orally twice daily.

Precautions

This medication should not be taken by those who are allergic to any of its ingredients. This medication contains lactose, so individuals with a genetic disease that causes them to be unable to digest lactose should avoid taking it. Those with a history of drug allergies or who have poor liver or kidney function, those undergoing dialysis, and older patients must be particularly cautious when using this medication. During the use of this medication, severe allergic reactions or shock symptoms may occur, so if you experience paleness of the face, a drop in blood pressure, or difficulty breathing, you must immediately stop taking it and go to the hospital. As liver function abnormalities may occur, if there are signs of increased liver enzymes or jaundice, you should stop taking the medication immediately and consult a doctor. There may be a decrease in blood cell counts leading to agranulocytosis or thrombocytopenia, so if symptoms like sore throat, fatigue, or fever arise, you should stop taking the medication and visit a hospital. Rarely, serious side effects such as skin rashes, seizures, or heart problems have been reported, so seek advice from a healthcare professional if any unusual symptoms arise. After taking this medication, you might experience various side effects such as constipation, diarrhea, headache, insomnia, dizziness, facial flushing, increased white blood cell count, increased eosinophils, decreased white blood cells, decreased red blood cells, decreased hematocrit, increased ALT (GPT), increased AST (GOT), increased Al-P, increased γ-GTP, increased T-Bil, increased LDH, and others, so you should closely monitor your condition. This medication may mask symptoms of gastric cancer or malignant tumors, so if symptoms such as weight loss, recurrent vomiting, or hematemesis occur, you must undergo tests. Older adults have weakened bodily functions, so the dose and frequency should be adjusted, and their condition must be meticulously monitored. Patients undergoing dialysis may have increased plasma concentrations of the drug, so it should be administered slowly starting at a low dose. Pregnant women should only take it when necessary and under the guidance of a physician, and breastfeeding women should avoid using this medication as it may be transmitted through breast milk. Safety for children has not been established, so it is best not to use it in pediatric patients. This medication should be kept out of reach of children and stored in its original container to maintain quality.

Side effects

  • Shock
  • Anaphylactic symptoms
  • Facial pallor
  • Hypotension
  • Generalized rash
  • Dyspnea
  • Liver function impairment
  • Jaundice
  • Agranulocytosis
  • Pharyngitis
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  • General malaise
  • Fever
  • Thrombocytopenia
  • Pancytopenia
  • Aplastic anemia
  • Seizures
  • Interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell's syndrome
  • Rhabdomyolysis
  • Heart block
  • Poor contraction
  • Constipation
  • Diarrhea
  • Hard stool
  • Nausea
  • Vomiting
  • Abdominal bloating
  • Anorexia
  • Headache
  • Insomnia
  • Drowsiness
  • Transient confusional state
  • Hallucinations
  • Consciousness disturbance
  • Dizziness
  • Dysgeusia
  • Sensation of heat
  • Facial flushing
  • Leukocytosis
  • Eosinophilia
  • Leukopenia
  • Erythrocytopenia
  • Reduced hematocrit
  • Elevated ALT
  • Elevated AST
  • Elevated Al-P
  • Elevated γ-GTP
  • Elevated T-Bil
  • Elevated LDH
  • Elevated TTT
  • Abnormal urinary protein
  • Elevated BUN
  • Elevated serum uric acid
  • Elevated Cl
  • Delayed menstruation
  • Elevated Na
  • Decreased K
  • Gynecomastia
  • Edema
  • Fatigue
  • Glossitis
  • Headache
  • Urticaria
  • Skin rash
  • Abdominal pain
  • Indigestion
  • Enteritis
  • Gastric ulcer
  • Erosive gastritis
  • Duodenitis
  • Bloating
  • Rhinitis
  • Upper respiratory infection
  • Bronchopneumonia
  • Tinea corporis
  • Carotid artery stenosis
  • Cough
  • Oral pharyngeal pain
  • Oral pharyngeal discomfort
  • Wet cough
  • Fatigue
  • Chest pain
  • Limb pain
  • Arthralgia
  • Neck pain
  • Itching
  • Acne
  • Contusion
  • Insomnia
  • Non-alcoholic fatty liver disease

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, at a temperature between 1 to 30 degrees Celsius at room temperature. Storing it this way will help maintain its effectiveness and prevent degradation.

Appearance and packaging

Appearance

White, round film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.