Amlodipine Tablet (Amlodipine Besylate)

Adult dose

Adults: Take 5 mg of amlodipine orally once daily, and the dose may be increased up to 10 mg daily depending on the patient's response. Adjust as appropriate based on age and symptoms.

This medication should not be used in certain patients. For example, it should not be administered to individuals with allergies to this drug or similar drugs, nursing women, patients with severe liver dysfunction, those with severe aortic stenosis, and patients in shock. It should also be used with caution in patients with severe hypotension, those requiring dialysis due to renal failure, the elderly, and women who are pregnant or may become pregnant. The drug is generally well tolerated, but side effects such as facial flushing due to vasodilation, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea may occur. Rarely, various adverse reactions such as excessive lowering of blood pressure, vascular inflammation, neurological symptoms, digestive issues, skin rashes, hair loss, and erectile dysfunction have been reported. Caution is necessary for patients with heart failure as pulmonary edema may increase, and patients with impaired liver function may require dose adjustment due to increased drug concentration in the body. This medication has a slow onset of action and is therefore not suitable for treating acute angina. It is known to have no significant effect on driving or operating machinery. Care must be taken when using this drug in combination with other medications. In particular, using it with grapefruit juice may enhance the hypotensive effect and is not recommended. Additionally, caution is necessary when combined with certain antibiotics, antihypertensive drugs, immunosuppressants, etc., and consultation with a doctor or pharmacist is advised. The safety of this drug during pregnancy or breastfeeding is not established, so use should be avoided if possible, and breastfeeding should be discontinued. Effectiveness has been confirmed in children aged 6 years and older; however, safety and efficacy are not known for those younger than this age. Overdose may result in severe hypotension and heart problems, requiring immediate medical attention, and emergency treatment may be necessary. This medication has been reported to have a low risk of carcinogenicity or genetic mutation even with long-term use.

Serious side effects

• Hives
• severe swelling (edema)
• jaundice
• severe allergic reactions
• severe skin reactions.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

Store this medication in a tightly closed container to prevent exposure to air or moisture. It is recommended to maintain the storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle