Ranitim 150 mg (Ranitidine Hydrochloride)

Adult dose

For adults, the recommended dose of ranitidine is 150 mg taken orally, twice daily, in the morning and at bedtime. 1) Gastric and duodenal ulcers: 150 mg can be administered twice daily or 300 mg once daily at bedtime. For patients with duodenal ulcers, 300 mg can be administered twice daily, in the morning and at bedtime. 2) Gastroesophageal reflux disease: Administer 150 mg twice daily for 8 weeks.

Child dose

For children aged 8 to 18 years, a single dose of 150 mg (2 mg per kg of body weight) can be administered up to twice a day.

This medication should not be used in patients with hypersensitivity to its ingredients. Patients with a history of acute porphyria should also not use this drug, as it may trigger acute attacks. It contains lactose, so it should not be administered to patients with lactose intolerance or related genetic issues. For patients with reduced kidney function, this medication may remain in the body longer, so dose adjustments or regimen modifications may be necessary. Patients with impaired liver function should also use this drug cautiously. Those with a history of drug hypersensitivity or elderly patients should be administered this medication with caution. Patients taking NSAIDs, especially the elderly or those with a history of peptic ulcers, require regular monitoring. It may mask symptoms of gastric cancer, so individuals over middle age with gastric ulcer or new or changed dyspeptic symptoms should confirm malignancy before use. Patients with gastric and duodenal ulcers positive for Helicobacter pylori should receive eradication therapy. This medication may rarely cause severe allergic reactions, such as anaphylactic shock, so if any abnormal symptoms occur during treatment, it should be discontinued immediately and managed accordingly. Symptoms of hypersensitivity such as hives, rash, and bronchospasm may also occur, requiring caution. Blood abnormalities, including fatigue, bleeding, and fever, may necessitate immediate medical evaluation. Rarely, liver dysfunction symptoms may occur, and use should be discontinued if jaundice or hepatitis symptoms appear. Cardiac rhythm disturbances, constipation, nausea, headache, dizziness, drowsiness, and confusion are also reported neurological abnormalities. Muscle pain, joint pain, and skin rashes may also rarely occur, so symptoms should be observed carefully. During treatment, monitor the course of the disease closely and use the minimum effective dose; if no effect is observed, it is advisable to switch to alternative therapy. Elderly patients, those with chronic lung disease, or diabetes mellitus face a heightened risk of pneumonia. Avoid driving or operating hazardous machinery in case of dizziness or drowsiness. This medication can affect the absorption or metabolism of other drugs, so dosage adjustments for concurrently taken medications may be necessary. In particular, the risk of bleeding is increased when taken with anticoagulants, thus regular blood tests to monitor status are essential. When taken with sucralfate, absorption may decrease, so a gap of at least 2 hours should be maintained between doses. The safety of this medication during pregnancy or lactation is not well established, so it should be used cautiously only when necessary. The safety for pediatric use has not been sufficiently confirmed, so caution is necessary. Elderly patients may have prolonged drug exposure due to decreased kidney function, necessitating dose reduction or increased dosing intervals. During treatment with this medication, false positives may appear in some urine tests, so be aware of the testing methods. No significant issues have been reported from overdose, but appropriate treatment, such as vomiting or gastric lavage, may be required. Store this medication out of reach of children, and do not transfer it to other containers, as this may compromise safety.

Serious side effects

Anaphylactic shock, hives, angioedema, chest pain, bronchospasm, hypotension, severe allergic reactions, rash, severe rash, blistering, exfoliation of the skin, pain in oral/ocular mucosa, severe skin adverse reactions, difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory issues, yellowing of the skin or eyes (jaundice), profound lethargy (liver abnormalities), confusion, seizures, sudden and severe symptoms

Mild side effects

Hives, angioedema, rash, fever, bronchospasm, hypotension, chest pain, granulocytopenia, elevated serum creatinine levels, leukopenia, thrombocytopenia, aplastic anemia, pure red cell aplasia, aplastic anemia, acquired immune hemolytic anemia, eosinophilia, temporary liver function abnormalities (increased AST, ALT, γ-GTP, ALP), bradycardia, heart block, tachycardia, vasculitis, constipation, nausea

This medication is sensitive to light and should be stored in a container that blocks light. It is best kept at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and prevent degradation.

Appearance

White, round, film-coated tablet

Package unit

Domestic use - 30 tablets - 30 tablets/bottle, Domestic use - 500 tablets - 500 tablets/bottle