Glustap 30 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once daily regardless of meals. Monotherapy: Start at 15 mg once daily, and if the effect is insufficient, it can be increased to 30 mg once daily. Combination therapy: - When combined with sulfonylureas, initial dose is 15 mg once daily. - When combined with metformin, initial dose is 15 mg once daily. - When combined with insulin, 15 mg once daily. Maximum recommended dose is

Child dose

There is no experience using this medication in children under 18 years of age, so its use is not recommended.

This medication is used for the treatment of type 2 diabetes and works to aid insulin action. However, it may exacerbate or cause heart failure in some patients, thus it should not be used in patients with existing heart disease or a history of heart failure. Patients should be closely monitored for signs of heart failure such as fluid retention leading to swelling, rapid weight gain, and shortness of breath while taking this medication, and should consult a doctor immediately if these symptoms occur. Furthermore, it should not be administered to patients with active bladder cancer or a history of bladder cancer, and if hematuria or urinary disturbances occur during treatment, the healthcare provider should be informed immediately. Patients with poor liver function or severe kidney dysfunction should also avoid this drug, and it is inappropriate for patients with diabetic ketoacidosis or type 1 diabetes. Women who are pregnant or may become pregnant should not take this medication, particularly premenopausal women due to its potential to stimulate ovulation, necessitating appropriate contraception. The risk of hypoglycemia may increase when this medication is used alongside other diabetes medications, so patients should be cautious of hypoglycemic symptoms and adjust dosages of other medications if necessary. Long-term use of this medication may lead to weight gain and edema, and the risk of fractures may also increase, so particularly female patients should pay attention to bone health. Regular monitoring of blood sugar and liver function tests during treatment is important, and any abnormal symptoms should be reported to a doctor immediately. Finally, the safety and efficacy of this medication have not been established in children, and caution should be exercised in the elderly.

Serious side effects

Congestive heart failure, symptoms of heart failure (including excessive and rapid weight changes, respiratory distress, and edema), severe edema, visible hematuria, urinary disorders, urgency, bladder cancer, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, abnormal respiration with cough and fever, jaundice of skin or eyes, general fatigue, sudden and severe headache, thunderclap headache, seizures

Mild side effects

• Upper respiratory infections
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infections
• back pain

This medication should be stored in a container that protects it from light and is airtight. Additionally, care should be taken to prevent moisture exposure, and the storage temperature should be maintained between 15 to 30 degrees Celsius, ideally around 25 degrees.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle