Lafrate 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Typically, 10 mg of Rabeprazole Sodium is administered orally once daily for adults. Depending on symptoms, 20 mg may be taken orally once daily. It should be administered for up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If not resolved after 8 weeks of treatment, further

This medication should not be administered to individuals who are allergic to specific ingredients or have had hypersensitivity reactions to benzimidazole derivatives. Patients who are allergic to penicillin-based or macrolide antibiotics should exercise caution when using this medication in conjunction with those antibiotics. It is also safer not to use this medication for individuals taking specific heart-related medications or antiviral agents, as well as for pregnant or nursing women. Patients with poor liver function or elderly individuals should use this medication more cautiously, and those with a history of drug allergies should also take care. This medication may cause adverse reactions such as rashes, itching, or other reactions in various areas including blood, liver, heart, digestive system, and nervous system, so if any abnormal symptoms occur, immediate consultation with a healthcare provider is advised. Regular monitoring of liver and blood tests is important during long-term use, as the risk of fractures may increase, thus caution is needed for prolonged administration. As this medication suppresses stomach acid secretion, there may be a slight increase in the risk of gastrointestinal bacterial infections, so if abnormal symptoms like diarrhea persist, diagnosis and treatment are necessary. Caution should be taken while driving or operating machinery as drowsiness may occur, and interactions with other medications may be present; therefore, it is essential to inform healthcare providers of any other medications being taken. Pregnant or nursing women should not use this medication, and elderly patients may experience more side effects due to decreased liver function, so treatment may be discontinued if symptoms occur. Safety for children has not been established, and there is limited experience in usage. In case of overdose, there are no specific antidotes, and appropriate treatment should be given based on symptoms; this medication should be swallowed whole and not chewed or crushed. When storing, keep this medication in a closed container away from children, and it is advisable not to transfer it to another container. Long-term use of this medication may cause vitamin B12 absorption disorders, so nutritional status should be monitored if necessary. Furthermore, this medication may affect the results of neuroendocrine tumor tests, so it may be necessary to discontinue it for a certain period before testing. Kidney diseases such as acute nephritis may arise, so if there are any abnormal symptoms related to kidney function, immediate consultation with healthcare providers is necessary.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, fulminant hepatitis, liver dysfunction, jaundice, angina, pulmonary embolism, thrombophlebitis, ventricular tachycardia, supraventricular tachycardia, myocardial infarction, conscious confusion, seizures, severe skin adverse reactions (toxic epidermal necrolysis, Stevens-Johnson syndrome), severe allergic reactions (anaphylaxis, shock), respiratory problems (dyspnea, asthma, apnea, respiratory depression), liver abnormalities (hepatic encephalopathy, jaundice)

Mild side effects

• Rash
• itching
• reduced red blood cells
• reduced white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• reduced lymphocytes
• anemia
• petechiae

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature to preserve its efficacy for a longer duration.

Appearance

Pale yellow round enteric coated tablet

Package unit

28 tablets/box [14 tablets/Alu Alu packaging x 2]