Avodart 0.5 mg Tablet (Dutasteride)

Adult dose

The recommended dose of this medicine is 1 tablet (0.5mg) once daily. Swallow this medicine whole without chewing or splitting it. This medicine may be taken with or without food. No dosage adjustment is necessary in patients with renal impairment or elderly patients. Since no data are available on administration of this medicine to patients with hepatic impairment, the recommended dose in these patients has not been established.

This medication should never be used by women, especially those who are pregnant or may become pregnant. This drug can be absorbed through the skin, so women must be very careful when handling this medication and should avoid touching broken or crushed pieces. Additionally, this drug is not to be used in children under 18 years old. Adult men who are planning to conceive should use this drug carefully under a doctor's supervision, as it may affect fertility. Patients with urinary problems or liver issues should also use this medication with caution. Since this drug is primarily metabolized in the liver, it should be administered carefully in patients with liver disease. Caution is needed when taken with strong CYP3A4 inhibitors as it may increase drug concentration. While taking this medication, there may be side effects related to sexual function such as erectile dysfunction, decreased libido, and ejaculation issues; some patients may also experience breast tenderness or gynecomastia. Though prolonged use of this drug has not shown an increased frequency of these side effects, rare cases of heart failure or breast cancer have been reported, hence regular check-ups are necessary. During treatment with this medication, blood donation should be avoided, and it is only possible to donate blood at least 6 months after the last dose. Moreover, this drug can reduce prostate-specific antigen (PSA) levels, affecting prostate cancer diagnosis; thus, regular PSA testing should be conducted before and during treatment. There is no specific antidote for overdose, so appropriate treatment should be provided based on symptoms. This medication should be kept out of the reach of children and is safest when stored in the original container. Finally, while it does not affect the ability to drive or operate machinery, caution should be exercised if any unusual symptoms occur.

• Erectile dysfunction
• decreased libido
• ejaculation disorder
• gynecomastia
• headache
• gastrointestinal discomfort and pain
• sexual dysfunction
• breast disorders
• dizziness
• rash

This drug should be stored in a tightly sealed container to prevent exposure to air or moisture, ideally at a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and prevent degradation.

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets/blister [30 tablets (10 tablets/PTP x 3)]