Rinatone M Tablet 2.5/850 mg

Adult dose

This medication is taken twice daily with meals. 1. If not being treated with metformin: The initial dose is 2.5/500 mg of this medication taken twice a day, one tablet per dose, which can be increased to 2.5/1000 mg taken twice a day, one tablet per dose. 2. In cases where blood sugar control is difficult with metformin alone: Linagliptin 2.5 mg twice daily and the existing dosage of metformin

This medication can cause a rare but serious side effect called lactic acidosis; therefore, patients with impaired kidney function or issues with heart or liver functions should not use it. Additionally, it should be avoided in patients with allergies to any ingredients of this medication or those with specific conditions such as type 1 diabetes, diabetic ketoacidosis, or acute myocardial infarction. As there is a risk of hypoglycemia, caution is needed when used with other antidiabetic agents such as insulin or sulfonylureas, and dosage adjustments may be necessary. Patients with decreased kidney function should have their kidney function tested periodically, and the medication should be temporarily discontinued under circumstances that pose a risk of acute kidney injury. This medication can cause skin conditions such as acute pancreatitis or bullous pemphigoid; therefore, if severe abdominal pain or skin abnormalities occur during treatment, consult a doctor immediately. It may lower vitamin B12 levels, so it's important to check for vitamin B12 deficiency during long-term use. Pregnant or nursing women should avoid using this medication, and it is not recommended for children and adolescents. Elderly patients often experience reduced kidney function, so adequate dosage adjustments and regular monitoring of kidney function are needed. This medication can interact with various drugs; therefore, inform your doctor or pharmacist if you are taking other medications. In case of overdose, there is a risk of lactic acidosis, and you should seek medical treatment immediately, possibly necessitating hemodialysis. Store this medication out of the reach of children, in a place avoiding moisture, and in its original container.

Serious side effects

• Urticaria
• severe swelling (edema)
• lactic acidosis
• angioedema
• increased blood pressure
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• severe allergic reactions

Mild side effects

Nasopharyngitis, hypersensitivity, angioedema, hypoglycemia, taste disorder, cough, decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rash, severe joint pain accompanied by disability, rhabdomyolysis, increased lipase, increased amylase, decreased vitamin B12 and deficiency, increased blood triglycerides, increased blood creatinine, itching, insomnia, depression,

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container while in use. Additionally, avoid storing it in places that are too hot or too cold, and it is recommended to keep it at room temperature between 1°C and 30°C.

Appearance

Bright orange, oval-shaped film-coated tablet with a convex surface on both sides

Package unit

60 tablets (10 tablets/PTP) x 6