Mizartan Plus Tablets 40/12.5 mg (Telmisartan, Hydrochlorothiazide)

Adult dose

For patients not adequately controlled with telmisartan alone, take this medication once daily with water, regardless of meals. It is recommended to adjust the doses of each component separately before switching to this medication, as the doses of its components are fixed. When clinically appropriate, direct switching from monotherapy to this medication may also be considered. - Telmisartan/Hydrochlorothiazide Combination 40/12.5 mg may be given to patients whose blood pressure is not adequately controlled with 40 mg of telmisartan. - Telmisartan/Hydrochlorothiazide Combination 80/12.5 mg may be given to patients whose blood pressure is not adequately controlled with 80 mg of telmisartan. - Telmisartan/Hydrochlorothiazide Combination 80/25 mg may be given to patients whose blood pressure is not adequately controlled with either 80 mg of telmisartan or 12.5 mg of hydrochlorothiazide alone or in combination. Sodium or volume depletion should be corrected before starting this medication. Renal impairment: For patients with mild to moderate renal impairment, dose adjustments are not necessary. This medication should not be given to patients with severe renal impairment (creatinine clearance <30 mL/min). Periodic monitoring of renal function is recommended. Liver impairment: Patients with mild to moderate liver impairment should use this medication with caution. The dosage should not exceed 40/12.5 mg per day. This medication should not be given to patients with severe liver impairment (see Precautions 2). Thiazide diuretics should be used with caution in patients with liver impairment. Elderly patients: Dose adjustments are not necessary. Pediatric patients: The safety and efficacy of this medication have not been established for patients under 18 years of age.

Child dose

The safety and efficacy of this medication have not been established for children under 18 years of age.

This medication can pose serious risks to the fetus during pregnancy, especially in the second and third trimesters, so discontinuation should be immediate upon confirmation of pregnancy. Patients who are allergic to the ingredients in this medication or have specific liver or kidney diseases should not use it. Elderly patients or those with certain heart, liver, or kidney conditions should use this medication with caution and be careful not to let blood pressure drop too low. Hydrochlorothiazide may increase sensitivity of the skin to sunlight, so exposure to ultraviolet radiation should be minimized during treatment, and any skin changes should be promptly discussed with a physician. Various side effects such as dizziness, headache, indigestion, and rash may occur during treatment; report any unusual symptoms to healthcare professionals immediately. Interactions may occur when used with other antihypertensive medications, certain diuretics, lithium, potassium supplements, etc., so notify your doctor of any other medications you are taking. Women who are pregnant or breastfeeding should not use this medication, and it should be avoided during breastfeeding due to the potential transfer into breast milk. In cases of overdose, symptoms such as hypotension, electrolyte imbalance, and dehydration may arise, thus seek medical attention immediately for appropriate treatment according to symptoms. This medication has not been established as safe and effective for children under 18 years of age, hence is not recommended. During use, keep out of reach of children, and store in a sealed condition until just prior to administration to maintain quality.

Serious side effects

• Hives
• angioedema (including fatal results)
• chest tightness
• difficulty breathing
• angioedema (including fatal results)
• angioedema
• sweating
• angioedema (fatal outcome)
• angioedema (fatal results included)
• angioedema

Mild side effects

Dizziness, diarrhea, cough, pharyngitis, sinusitis, hypokalemia, hyperuricemia, hyponatremia, anxiety, depression, insomnia, sleep disorders, paresthesia, visual impairment, blurred vision, vertigo, tachycardia, arrhythmia, hypotension, orthostatic hypotension, lung inflammation, gastrointestinal disorders (dry mouth, bloating, abdominal pain, constipation, indigestion, vomiting, gastritis), sweating, rash, hives, back pain, muscle cramps, myalgia, arthralgia,

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help safely preserve the medication's effectiveness.

Appearance

White or whitish oval tablets

Package unit

30 tablets (10 tablets/Alu-Alu * 3)