Dimendone Tablet 5 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As donepezil hydrochloride, administer 5 mg orally once daily before bedtime. For 4-6 weeks, administer a dosage of 5 mg. After evaluating clinical response during this period, it may be increased to 10 mg. When increasing to 10 mg per day, caution should be taken regarding gastrointestinal adverse reactions. For underweight female patients aged 85 years and older, the daily dosage should not exceed 5 mg and careful monitoring is needed.

Child dose

There is no experience regarding the use in children.

This medication should not be used by individuals who are allergic to certain components or by women who are pregnant or breastfeeding, as well as those with genetic lactose-related disorders. Special caution is required for those with heart disease or abnormal heart rhythms, those with a history of peptic ulcers or who are taking non-steroidal anti-inflammatory drugs, those with asthma or pulmonary diseases, and those with extrapyramidal disorders such as Parkinson's disease when using this medication. Serious side effects like dizziness, nausea, vomiting, diarrhea, heart problems, liver function abnormalities, seizures, muscle pain, and difficulty breathing may occur while taking this medication, so it is essential to consult a doctor immediately if abnormal symptoms arise. This medication is used for the treatment of Alzheimer's type dementia, and the dosage may be adjusted or discontinued based on regular assessment of treatment effectiveness. Patients with heart disease or a history of QT interval prolongation should undergo regular examinations of heart condition while taking this medication, and caution is needed when taking it alongside other medications that may affect the heart. This medication may increase gastric acid secretion and enhance gastrointestinal motility, so individuals with a history of peptic ulcers should monitor for symptom exacerbation. Caution is necessary when driving or operating machinery as dizziness or fatigue may occur, especially when adjusting the dosage. Pregnant or breastfeeding women are advised not to use this medication, and if necessary, should consult with healthcare professionals before use. Safety has not been established for use in children, so it should not be administered to them. This medication may affect liver and kidney function test results, necessitating regular assessments. In case of overdose, hazardous symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, requiring immediate medical attention, and atropine may be used as an antidote. This medication has many interactions with other drugs; therefore, when taken with heart medications, antibiotics, antidepressants, antipsychotics, etc., it is crucial to inform healthcare professionals.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, chest tightness, cold sweating, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, loss of consciousness, visual disturbances, paralysis, urinary symptoms.

Mild side effects

• Headache
• dizziness
• diarrhea
• nausea
• vomiting
• loss of appetite
• insomnia
• drowsiness
• muscle pain
• fatigue

This medication should be stored in an airtight container and kept at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a long time.

Appearance

This medication is a white, round film-coated tablet.

Package unit

100 tablets/bottle, 30 tablets/bottle