Tobika Tablet 5/40 mg

Adult dose

This medication is administered once daily with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dosing is as follows: - 5/20 mg: Give to patients whose blood pressure is not adequately controlled with amlodipine 5 mg or olmesartan medoxomil 20 mg monotherapy. - 10/20 mg: Give to patients whose blood pressure is not adequately controlled with olmesartan medoxomil 20 mg monotherapy.

Child dose

Safety and efficacy have not been established in pediatric patients under 18 years of age.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to this medication or severe liver disease, severe aortic stenosis, bile duct obstruction, those on dialysis, patients in shock, and certain diabetic patients should not take this medication. When this drug is first administered to patients who are depleted of fluids or salt, hypotension may occur, so their condition should be closely monitored, and appropriate measures should be taken if hypotension develops. This drug has a vasodilating effect, and acute hypotension may occur in some patients, so caution is advised. Patients with severe heart disease should use caution as cardiac symptoms may worsen during the use of this medication. Patients with weakened kidney function or kidney disease should be cautious as this medication may further worsen kidney function. Patients with reduced liver function should take this medication with consideration of their liver function status since it is metabolized in the liver. During treatment, side effects like dizziness, headache, hypotension, swelling, digestive disturbances, and rash may occur; persistent symptoms should be discussed with healthcare professionals. This medication may interact with other medications, so patients should inform their healthcare providers of any other medications they are taking. In particular, taking this medication with grapefruit juice may enhance its effect, so it is recommended to avoid it. Women who are pregnant or breastfeeding should avoid taking this medication; if breastfeeding, they should consider whether to discontinue the medication or breastfeeding carefully. It is not recommended for children as safety and efficacy have not been established in pediatric patients under 18 years of age. Elderly patients may have reduced kidney and liver function, so treatment should start at a low dose with careful monitoring. In cases of overdose, symptoms such as hypotension or arrhythmia may occur, requiring immediate medical attention. This medication should be stored in a tightly sealed container to avoid exposure to light and moisture and kept out of reach of children.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, urticaria, severe skin reactions, yellowing of the skin or eyes (jaundice), liver dysfunction (jaundice), severe swelling or urinary abnormalities, significantly decreased urine output, increased blood pressure, sudden and extremely severe headaches, seizures, confusion, vision disturbances, paralysis, shortness of breath or difficulty breathing, asthma attacks, breathing difficulties associated with cough and fever

Mild side effects

• Hyperkalemia
• decreased libido
• dizziness
• headache
• orthostatic hypotension
• drowsiness
• dysesthesia
• decreased sensation
• syncope
• lightheadedness

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature to keep its efficacy and safety well preserved.

Appearance

Pale yellow round film-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)