Celebrex 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be taken regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be used with caution in individuals who consume large amounts of alcohol daily as it may increase the risk of gastrointestinal bleeding; consultation with a doctor or pharmacist is essential. Use should be limited to the minimum dosage and short duration as it may increase the risk of cardiovascular disease; seek immediate medical consultation if cardiovascular symptoms occur. Special care is needed for the elderly as gastrointestinal perforation, ulcers, bleeding, etc., may occur; immediate assessment and treatment are required if gastrointestinal symptoms appear. Patients with a history of hypersensitivity or allergies, severely impaired liver or kidney function, pregnant or breastfeeding women, and those with certain diseases should not take this medication. Patients with weak liver or kidney function, asthma, heart failure, or a history of hypertension should be treated with caution and require regular monitoring. This medication may have various side effects; if dizziness, dyspepsia, skin rash, or difficulty breathing occurs while taking it, inform medical personnel immediately. As this medication has many drug interactions, inform healthcare providers of any other medications being taken, especially caution is needed when taken with antihypertensives, anticoagulants, or antidepressants. Pregnant women or those planning pregnancy should avoid this medication, and breastfeeding mothers should either discontinue breastfeeding or stop taking the medication. The elderly are at a higher risk of reduced kidney and liver functions, requiring careful monitoring and dosage adjustment while taking this medication. If taken long-term, regular blood tests and liver/kidney function tests should be performed, and if any abnormalities are found, use should be discontinued. In case of overdose, symptoms like nausea, vomiting, and drowsiness may occur; seek medical attention immediately for appropriate treatment. Keep this medication out of reach of children and avoid transferring it to other containers.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, cerebrovascular accident, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confused state, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevation of liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injuries, folliculitis, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, frequency of urination, nephrolithiasis, urinary incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, back pain, allergic exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, insomnia, loss of appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infections, herpes simplex, wound infection, gingivitis, herpes simplex virus, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, chest neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, earache, hearing impairment, hepatic dysfunction, increased ALT, increased AST, elevated γ-GTP, increased ALP, positive urine urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatocellular necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, elevated alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthrosis, skeletal anomalies, myalgia, cervical strain, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various parts, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, folliculitis, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, frequency of urination, nephrolithiasis, urinary incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, hepatocellular necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, female infertility

This medication should be stored in a tightly sealed container to prevent air and moisture exposure, and it is recommended to store it at room temperature between 15 to 30 degrees Celsius. Storing it this way helps maintain the medication's efficacy for a longer period.

Appearance

White capsule filled with a white to off-white powder with blue stripes on the top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle