Medication info

Darim Atorvastatin 40 mg Tablet (Atorvastatin Calcium Trihydrate)

Prescription medicationTabletExpired
Ingredient · strength
Atorvastatin Calcium Trihydrate›43.38mg / 1 tablet
Manufacturer / importer
(주)다림바이오텍
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 120 tablets/bottle
Approval status
Expired

MFDS item code 201903323 · Approved 2019.05.22

This product's status changed to Expired on 2024.05.22. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Reduces the risk of myocardial infarction and stroke, and improves hyperlipidemia
Who uses it
Adults
Adult dosage
Atorvastatin is administered once daily, at any time, with or without food within a range of 10 to 80 mg. The recommended initial dose is 10 mg once daily, which can be increased to 20 mg or 40 mg if greater reductions in LDL cholesterol are needed. Lipid levels should be analyzed within 2 to 4 weeks after starting treatment to adjust the dosage accordingly. For patients with homozygous familial hypercholesterolemia, the initial dose is once daily.

Ingredients

Manufacturer
(주)다림바이오텍

Efficacy & effects

Reduces the risk of myocardial infarction and stroke, and improves hyperlipidemia

  • Myocardial infarction
  • stroke
  • revascularization procedure
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • abetalipoproteinemia
  • elevated serum triglycerides
View approved original text

This medication helps reduce the risk of cardiovascular diseases. It decreases the risk of myocardial infarction and stroke and has preventive effects against revascularization procedures and angina. It shows positive effects, particularly in adults with multiple risk factors and patients with type 2 diabetes. Additionally, it is used to lower cholesterol and triglyceride levels in patients with primary hyperlipidemia and dyslipidemia while increasing HDL, the good cholesterol. It can also be utilized when dietary adjustments are not sufficient, improving cardiovascular health through lipid regulation. Overall, it is effectively used in the treatment of heart disease and hyperlipidemia.

Dosage and Administration

Adult dosage

Atorvastatin is administered once daily, at any time, with or without food within a range of 10 to 80 mg. The recommended initial dose is 10 mg once daily, which can be increased to 20 mg or 40 mg if greater reductions in LDL cholesterol are needed. Lipid levels should be analyzed within 2 to 4 weeks after starting treatment to adjust the dosage accordingly. For patients with homozygous familial hypercholesterolemia, the initial dose is once daily.

Precautions

This medication may result in muscle-related side effects, so if there are symptoms such as muscle pain or weakness, discontinue use immediately and consult a doctor. This medication can affect liver function, so it should not be used in patients with liver disease or elevated liver enzyme levels, and regular liver function tests should be conducted. Pregnant women, women who may become pregnant, and breastfeeding women should not take this medication, and women of childbearing age should practice appropriate contraception while on this medication. Children, especially those under 10 years old, should not use this medication, and long-term safety in individuals under 18 years has not been established. Older adults or patients with impaired kidney function should be closely monitored for the risk of muscle abnormalities and rhabdomyolysis while taking this medication. This medication can interact with various drugs; therefore, it is crucial to inform your doctor or pharmacist about any other medications you are taking, especially when used in conjunction with specific antibiotics, antifungals, antivirals, or some hyperlipidemia medications. No specific antidote is available for overdose; treatment should be symptomatic, with monitoring of liver function and muscle damage. This medication should be stored out of reach of children and not transferred to a different container from its original packaging. If symptoms such as muscle pain, weakness, or fever occur while taking this medication, inform healthcare personnel immediately and get tested. Additionally, avoid consuming grapefruit juice while on this medication, as it may increase blood levels and the risk of side effects.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/eye mucosal pain, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities along with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, swelling.

Mild side effects

  • Weakness
  • fatigue
  • chest pain
  • peripheral edema
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
  • loss of appetite
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  • constipation
  • abdominal bloating
  • indigestion
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • oropharyngeal and laryngeal pain
  • nosebleeds
  • insomnia
  • nightmares
  • headache
  • dizziness
  • sensory changes
  • sensory loss
  • taste disturbance
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container, protected from air and moisture. It is important to maintain storage temperatures between 1 to 30 degrees Celsius to preserve its effectiveness.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 120 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.