Ugli Tablet 15 mg (Pioglitazone Hydrochloride)

Adult dosage

This medication is administered orally once daily without regard to meals. As monotherapy, it is initiated at 15 mg orally once daily, and if adequate effectiveness is not achieved, the dose may be increased to 30 mg once daily. In combination therapy, 15 mg orally once daily is also administered. The maximum recommended dosage does not exceed 30 mg once daily.

Children's dosage

There is no experience in pediatric patients under 18 years of age, so use is not recommended.

This medication is used for treating type 2 diabetes and requires insulin to lower blood sugar levels. It may worsen or newly induce heart failure, thus it should not be used in patients with heart failure, and symptoms of heart failure such as sudden weight gain, shortness of breath, and edema should be closely monitored during treatment. Fluid retention may occur, which can lead to swelling, so if there is severe swelling or signs of heart failure, consult a doctor immediately. This medication should not be administered to patients with bladder cancer or a history of bladder cancer, and if symptoms such as hematuria or urinary difficulties develop during treatment, inform a physician immediately. Patients with impaired liver function or severe renal impairment should generally avoid this medication, and if symptoms of liver dysfunction appear, treatment should be stopped, and medical consultation is advised. The risk of hypoglycemia may increase when used with other blood glucose-lowering agents, especially insulin or sulfonylureas, so symptoms of hypoglycemia should be monitored, and doses of other medications may need adjustment. In premenopausal women, this medication may promote ovulation, increasing the risk of pregnancy, so appropriate contraception should be employed. Use with caution in elderly patients or those with reduced kidney function, and regular blood glucose and liver function tests are essential. During treatment, weight gain and edema may occur, so monitor weight changes closely, and consult a doctor if any abnormalities are observed. No specific symptoms may present in case of overdose; however, appropriate treatment and observation based on clinical symptoms are necessary. This medication is not recommended for use in children, as safety and efficacy have not been established. Lastly, this medication must be taken according to a physician's prescription and instructions, and any uncomfortable symptoms or adverse reactions experienced during use should be reported to medical staff immediately.

Serious side effects

Congestive heart failure, worsening of heart failure, edema (peripheral edema, generalized edema, pitting edema, fluid retention), severe edema, cardiac dysfunction, stroke, myocardial infarction, chest tightness, difficulty breathing, dyspnea, severe liver abnormalities (liver failure, jaundice), hives, severe allergic reactions, hives, hypertension, stroke, severe neurological symptoms, severe skin adverse reactions, bladder cancer, urinary abnormalities, cardiovascular death, severe low

Mild side effects

• Upper respiratory tract infections
• headaches
• sinusitis
• muscle pain
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infections
• back pain

This medication should be stored in a light-resistant, airtight container and kept away from humid areas. The storage temperature should be generally between 15 to 30 degrees Celsius, ideally at about 25 degrees Celsius in a cool place.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle