Evanstin Tablet 10/10 mg

Adult dose

This medication is administered once daily in the evening, regardless of meals. For patients with primary hypercholesterolemia, the dosing range is 10/10 mg to 10/40 mg daily, with the generally recommended initial dose being 10/20 mg daily. Patients with less need for LDL cholesterol reduction may start at 10/10 mg daily. For patients with homozygous familial hypercholesterolemia, the recommended dose is 10/40 mg once daily in the evening.

This medication is used to lower cholesterol levels in the blood. When taking this medication, muscle-related issues may occur; therefore, if muscle pain or weakness develops, patients should inform their doctor immediately. Especially when taking this medication at high doses or in combination with certain drugs, the risk of myopathy or rhabdomyolysis (serious muscle damage) is significantly increased. Patients with poor liver function or active liver disease should not use this medication. Pregnant or nursing women should also avoid using this medication, and women of childbearing potential should discuss with a doctor before taking it. Additionally, this medication can interact with certain drugs; thus, it is essential to inform the doctor or pharmacist of any other medications being taken. Especially, when taken with medications that interfere with the metabolism of this medication in the liver, the risk of muscle damage may increase. This medication is restricted for use in children only for those aged 10 years and older, especially in adolescents aged 10-17, and is not recommended for children under 10 years. Elderly patients may respond more sensitively to this medication, requiring caution. During treatment, regular blood tests must be performed to monitor liver function and muscle condition, and medical consultation should occur for any abnormal symptoms. In cases of overdose, there is no specific antidote, and appropriate treatment should be provided based on symptoms. While this medication may help reduce the risk of cardiovascular disease by controlling cholesterol levels, it is crucial to adhere to all precautions while taking it.

Serious side effects

Urticaria, angioedema, rash, pancreatitis, cholelithiasis, cholecystitis, anaphylaxis, lupus erythematosus-like syndrome, polymyositis, dermatomyositis, vasculitis, purpura, thrombocytopenia, leukopenia, hemolytic anemia, positive antinuclear antibody, persistent elevation of serum aminotransferase levels, hepatitis, cholestatic jaundice, cirrhosis, fulminant hepatic necrosis, liver cancer, liver failure, toxic epidermal necrolysis (Lyell's syndrome), mucocutaneous syndrome.

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory tract infection
• muscle pain
• limb pain
• fatigue
• nausea
• abdominal pain
• constipation

This medication is sensitive to air and moisture, so it should be stored in a tightly closed container. It is essential to maintain a storage temperature between 1 degree and 30 degrees Celsius to preserve the medication's effectiveness.

Appearance

White to light yellow, biconvex, rectangular tablet

Package unit

30 tablets (10 tablets/PTPX3)