Megaroxofen Tablets (Sodium Loxoprofen Hydrate)

Adult dose

Administer 60 mg of sodium loxoprofen (anhydrous) orally three times a day. For single-dose therapy, 60-120 mg should be taken orally. In principle, 180 mg can be administered maximum per day, in two doses. It is preferable to avoid taking on an empty stomach. Dosage may be adjusted based on symptoms.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages a day, so it is essential to consult a doctor or pharmacist before use. Caution is needed for individuals with cardiovascular diseases or risk factors, as there may be an increased risk of cardiovascular problems such as myocardial infarction or stroke when taking this medication. This medication can cause severe adverse reactions such as ulcers, bleeding, or perforation in the gastrointestinal tract, particularly in the elderly, so gastrointestinal symptoms should be monitored closely during treatment. Individuals with a history of peptic ulcers, severe liver or kidney disorders, congestive heart failure, or specific allergies should not take this medication, and pregnant women in late pregnancy or breastfeeding should avoid its use. Those with a previous history of peptic ulcers or blood disorders, elderly patients, and hypertensive individuals should use this medication cautiously and consult a doctor immediately if any adverse reactions occur during use. This medication may provoke hypersensitive reactions such as skin rashes, hives, breathing difficulties, and low blood pressure; if these symptoms occur, stop taking it immediately and inform healthcare professionals. Gastrointestinal symptoms may include abdominal pain, nausea, vomiting, and diarrhea, and in severe cases, bleeding symptoms such as hematemesis or bloody stools may occur, requiring careful attention. Dizziness or drowsiness may occur when taking this medication; caution is advised when driving or operating machinery. Long-term use may lead to liver function abnormalities or reduced kidney function, so regular blood tests and liver and kidney function tests are necessary. This medication should not be taken in combination with other non-steroidal anti-inflammatory drugs, as the risk of side effects may increase; avoid co-administration, and inform your healthcare provider about any medications being taken. Women in early or mid-pregnancy should use this medication cautiously, and it should not be taken in the late stages of pregnancy, as it may severely impact the fetus. The safety for pediatric use has not been established, so it is advisable to avoid use in children. Elderly patients are at higher risk for the occurrence of side effects, so extra caution is required during treatment. This medication should be stored out of reach of children, and transferring it to another container is not recommended, as it helps maintain quality.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth and eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory anomalies accompanied by cough or fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, decreased urine output.

Mild side effects

• Occasionally
• rashes
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is recommended to store it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer duration.

Appearance

White round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle