Linadia Duo Tablet 2.5/1000 mg

Adult dose

The dosage of this medication should be determined based on each patient's treatment regimen, efficacy, and tolerance, not exceeding the maximum recommended dose of 2.5 mg of linagliptin and 1000 mg of metformin, administered twice daily with meals. 1. If there is no previous experience with metformin treatment: The initial dose is 2.5/500 mg taken twice daily, one tablet per dose, and it may be increased to 2.5/1000 mg, one tablet taken twice daily.

This medication can cause a rare but serious side effect called lactic acidosis and should not be used in patients with impaired kidney function or problems with heart or liver function. People who are allergic to this drug's active ingredient or components, patients with type 1 diabetes, acute myocardial infarction, or congestive heart failure, as well as pregnant or breastfeeding women should not take this medication. There is a risk of hypoglycemia, so blood sugar should be closely monitored when used with insulin or sulfonylureas, and dosages should be adjusted as necessary. Elderly patients with impaired kidney function or specific medical conditions should undergo regular kidney function tests, and treatment should be discontinued or adjusted if kidney function deteriorates. This medication should be temporarily discontinued during acute infections, dehydration, severe trauma, pre- and post-surgery, or during the use of radiocontrast agents, and treatment should be resumed once the condition stabilizes. This drug can cause side effects such as pancreatitis and skin disorders like bullous pemphigoid; therefore, if you experience persistent abdominal pain or blisters on the skin, you should notify your doctor immediately. While taking this medication, side effects such as gastrointestinal disturbances, taste disorders, fatigue, headaches, rashes, and hypoglycemia may occur, so if any abnormal symptoms arise, consult with a healthcare professional. Women planning a pregnancy or who are pregnant should not take this medication and should choose other safe methods for blood sugar control. This medication is not recommended for children under 10 years old or teenagers, and elderly patients may need dosage adjustments based on kidney function. It is advisable to avoid alcohol as it may increase the risk of lactic acidosis, and check with your doctor or pharmacist if you are taking other medications that may interact with this drug. When taking this medication, keep it out of reach of children and store it in a dry place. In case of overdose, remove the drug from the gastrointestinal tract, and if necessary, treatments like dialysis may be required, so visit a medical institution immediately.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, bullous pemphigoid, liver dysfunction abnormalities due to liver impairment, acute myocardial infarction, heart failure, angina pectoris, acute coronary syndrome, unstable angina, cardiac arrest, acute kidney injury, end-stage renal disease, dyspnea, asthma, respiratory problems, acute cholangitis, acute cholecystitis, cholangitis, hepatitis, severe rash with high fever, blistering, skin peeling, oral/ocular mucosal pain, severe allergic reactions.

Mild side effects

• Pharyngitis
• hypersensitivity
• reduction and deficiency of Vitamin B12
• taste disturbance
• cough
• decreased appetite
• diarrhea
• constipation
• nausea
• vomiting

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature at room temperature between 1 and 30 degrees Celsius. This will help preserve the drug's effectiveness for a longer period.

Appearance

Bright pink, double convex, oval film-coated tablet

Package unit

30 tablets/bottle, 60 tablets/bottle, 100 tablets/bottle, 200 tablets/bottle