Rafdin Tablet 10 mg (Lafutidine)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine twice daily, orally in the morning and before bedtime. Clinical studies involving treatment for up to 8 weeks showed that most ulcers healed within 8 weeks, although the healing period may occasionally vary between patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine twice daily, orally in the morning and before bedtime. Clinical studies involving treatment for up to 6 weeks showed that most ulcers healed within 6 weeks, although the healing period may occasionally vary between patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. Clinical studies involving treatment for up to 2 weeks showed that most lesions healed within 2 weeks, although the healing period may occasionally vary between patients. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery), administered orally. 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

This medication should not be used by patients who are allergic to certain ingredients. It contains lactose, so caution is needed for patients with lactose intolerance or genetic metabolic disorders. Patients with allergies to soybean oil, beans, peanuts, etc. should also refrain from taking this medication. Patients who have previously experienced hypersensitivity reactions to medications should use this product with caution. Patients with liver or kidney issues, especially those on dialysis or the elderly, should be particularly careful when taking this medication. Patients with lipid metabolism disorders or who use lipid emulsions should take this medication cautiously. Severe allergic reactions such as anaphylaxis may occur, so if any unusual symptoms appear, immediately discontinue use and inform medical personnel. Liver dysfunction or jaundice symptoms may occur, so it is important to regularly check liver status. If symptoms related to decreased blood cell counts such as sore throat, general fatigue, or fever appear, immediate consultation with a healthcare provider is necessary. Rarely, serious side effects have been reported, such as skin rash, seizures, nephritis, heart problems, so swift action is required if unusual symptoms occur. Gastrointestinal symptoms such as constipation, diarrhea, nausea, vomiting, abdominal bloating, and loss of appetite may occur. Central nervous system symptoms can include headache, insomnia, drowsiness, reversible disorientation, hallucinations, consciousness disturbance, and dizziness. Cardiovascular symptoms include palpitations, warmth, and facial flushing. Blood tests may reveal an increase or decrease in white blood cells, decreased red blood cell counts, and possible elevated liver function test results, thus periodic testing is necessary. Symptoms of kidney function abnormalities have also been reported, so kidney status should be monitored. This medication may mask or delay the diagnosis of malignant tumors; therefore, if symptoms like weight loss, recurrent vomiting, or hematemesis occur, testing is essential. If stomach cancer is suspected, treatment should be discontinued upon confirmation after initial testing. During treatment, the patient's condition should be continuously monitored, and if no effect is observed, it is advisable to switch to another therapy. Patients at risk for lipid overload should regularly check plasma lipid levels and adjust the dose if necessary. The elderly may have decreased physical function, thus dosage and intervals should be carefully monitored. Patients on dialysis may experience increased drug concentrations in the blood, so treatment should start at a low dose and be administered cautiously. Pregnant women should use the medication only if the benefits outweigh the risks as judged by a physician, and it is safest not to administer it to breastfeeding women. Safety for children has not been established, so caution is required for use. Store out of reach of children, and do not transfer the medication from its original container to another container.

• Shock
• symptoms of anaphylaxis
• pallor
• hypotension
• generalized rash
• dyspnea
• hepatic impairment
• jaundice
• agranulocytosis
• pharyngitis

This medication may be sensitive to air and moisture, so it must be stored in a tightly closed container. It is best to maintain room temperature between 1 to 30 degrees Celsius. Doing so will ensure the medication's efficacy and safety.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle