Sebitan HCT Tablet 10/40/12.5 mg

Adult dose

This medication should be taken as one tablet once daily, with or without food, preferably at the same time every day (e.g., in the morning). The recommended dosing regimen is adjusted with stages of 5/20/12.5 mg, 5/40/12.5 mg, 5/40/25 mg, 10/40/12.5 mg, and 10/40/25 mg. The maximum dosage is 10/40/25 mg. Patients with renal impairment may require lower doses.

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years have not been established, and its use is not recommended.

This medication should not be taken during the second and third trimesters of pregnancy as it can cause serious harm to the fetus and newborn. Patients with allergies to this medication or its components, or those with certain heart, kidney, or liver diseases, should not take this medication. Patients with excessively low blood pressure or acute heart failure should also avoid this medication. Patients with decreased blood volume or salt deficiency may experience hypotension upon initial use, so caution is required and appropriate measures should be taken immediately if symptoms occur. Patients with poor kidney function may experience deterioration of kidney function when taking this medication, thus regular blood tests and monitoring are needed. Patients with severe liver function impairment or bile duct obstruction are not recommended to take this drug. This drug lowers blood pressure, so caution should be taken while driving or operating machinery, as dizziness may occur. While taking this medication, serum electrolyte levels, particularly potassium, sodium, calcium, and magnesium levels should be regularly monitored. This medication may commonly cause side effects such as peripheral edema, headache, dizziness, upper respiratory infections, rhinitis, urinary tract infections, sialadenitis, leukopenia, thrombocytopenia, bone marrow suppression, neutropenia/agranulocytosis, hemolytic anemia, aplastic anemia, drug hypersensitivity, hyperkalemia, hypokalemia, appetite loss, diabetes, hypercalcemia, hyperglycemia, hypomagnesemia, hyponatremia, hypochloremia, hypertriglyceridemia, hypercholesterolemia, and hyperuricemia. Due to the presence of Hydrochlorothiazide, there may be rare severe respiratory issues like acute respiratory distress syndrome, so if breathing difficulties or sudden symptoms occur, immediate consultation with medical personnel is required. This medication interacts with other blood pressure medications, diuretics, lithium, non-steroidal anti-inflammatory drugs (NSAIDs), so it is crucial to inform your healthcare provider about any other medications being taken. Women who are pregnant or planning to become pregnant should consult their doctor before starting this medication, and breastfeeding mothers are recommended to discontinue breastfeeding when taking this medication. The safety and efficacy of this medication in patients under 18 years have not been established, so it is not recommended for use. Elderly patients should start at a lower dose considering the possibility of decreased kidney and liver function and should be administered cautiously. In cases of overdose, severe hypotension and heart issues can occur, so the prescribed dosage must be strictly followed, and in cases of overdose, immediate medical attention should be sought. This medication should be stored in a tightly sealed container, away from moisture, heat, and direct sunlight, and out of reach of children.

Serious side effects

Hives, severe swelling (edema), allergic reactions, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues associated with cough and fever, jaundice, severe lethargy throughout the body, liver abnormalities, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory infections
• rhinitis
• urinary tract infections
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage will ensure the safety and efficacy of the medication.

Appearance

Round film-coated tablets with a grayish-red color

Package unit

Domestic - 30 tablets (10 tablets/Alu-Alu X3) - 30 tablets/PTP