Diacerein Capsule (Diacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein orally in 1∼2 divided doses after meals. The dose may be adjusted according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used in patients with inflammatory bowel disease or intestinal obstruction syndrome. It should also be avoided in cases of unexplained abdominal pain. Patients allergic to this drug, its ingredients, or Rhein class drugs should not take it. Patients with liver disease or a history of liver disease should preferably not use this drug. Children under 15 years of age should not take this drug. As it contains lactose, patients with genetic issues such as galactose intolerance, lactose enzyme deficiency, or glucose-galactose malabsorption should not be given this drug. Patients with a history of small intestine or colon disease should use this drug with caution and may need to avoid it in certain cases. It is advisable for pregnant or breastfeeding women to avoid this medication. Elderly patients over 65 years of age should reduce the dosage of this medication. This drug may cause gastrointestinal symptoms such as diarrhea, loose stools, and abdominal pain, and serious issues like gastrointestinal bleeding, ulcers, or perforations may occur with prolonged use. If diarrhea is severe, dehydration or electrolyte imbalance may occur, so caution is advised. Allergic reactions such as itching, rashes, or eczema may appear on the skin. It can affect liver function, potentially leading to elevated liver enzyme levels, so liver health should be checked regularly. For long-term use, it must be taken under a doctor's instruction, and if diarrhea occurs, the medication should be stopped immediately and a doctor consulted. Taking this medication with antacids or drugs containing calcium, magnesium, or aluminum may interfere with its absorption, so it should be separated by at least 2 hours. Taking it with diuretics may enhance the diuretic effect, potentially resulting in dehydration or hypokalemia, so caution is needed. When taken with cardiac glycosides, the risk of arrhythmias may increase, so caution is advised. During pregnancy, it should be avoided as it may affect fetal bone formation, and during breastfeeding, it should be avoided as it can be transmitted in small amounts in breast milk. In case of overdose, severe diarrhea may occur, which may require appropriate treatment such as electrolyte supplementation.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rash, eczema, serum elevation of liver enzymes

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It should also avoid excessively hot or cold places and be stored at room temperature between 1 to 30 degrees Celsius.

Appearance

A hard capsule with a white upper part and a yellow lower part, filled with a yellowish-brown content.

Package unit

30 capsules/bottle, 500 capsules/bottle